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ESE-3转录因子与肿瘤发生

吴家焱 陶永清 韩之波

基础医学与临床2018,Vol.38Issue(3):400-404,5.
基础医学与临床2018,Vol.38Issue(3):400-404,5.

ESE-3转录因子与肿瘤发生

ESE-3 transcription factor and tumorigenesis

吴家焱 1陶永清 2韩之波1

作者信息

  • 1. 天津商业大学 生物技术与食品科学学院 天津市食品生物技术重点实验室,天津300134
  • 2. 中国科学医学院 血液病医院 (血液研究所),天津300041
  • 折叠

摘要

Abstract

ESE-3 belongs to the epithelium-specific ETS transcription factor subfamily of ETS (E26) located in chromosome 11p12. It belongs to the transcriptional regulation factor which forms transcription complexes with its effector molecules, enhancing or inhibiting transcription of different downstream target genes. The expression of ESE-3 is abnormal in many kinds of tumors, such as colon cancer, pancreatic cancer, prostate cancer, breast cancer and so on. It suggests that ESE-3 plays an important role on the pathogenesis of various tumors.

关键词

ESE-3因子/肿瘤

Key words

ESE-3 factors/cancer

分类

医药卫生

引用本文复制引用

吴家焱,陶永清,韩之波..ESE-3转录因子与肿瘤发生[J].基础医学与临床,2018,38(3):400-404,5.

基金项目

国家自然科学基金(31470951) (31470951)

天津市创新团队项目(TD-12-5049) (TD-12-5049)

基础医学与临床

OACSCDCSTPCD

1001-6325

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