摘要
Abstract
Objective To compare the efficacy of rabeprazole and pantoprazole in the treatment of peptic ulcer bleeding.Methods Ninety patients with peptic ulcer in this hospital from January to December 2016 were selected and randomly divided into the two groups,45 cases in each group.The control group used the rabeprazole therapy,while the study group adopted the pantoprazole treatment.Then clinical effects and phar-maceutical economic were compared between the two groups.Results The effective rate of the control group was higher than that of the study group,but the difference was not statistically significant(P>0.05);in the comparison of abdominal pain score,burning sensation score and sour regurgitation score had no statistical difference between the two groups(P>0.05);the plasma viscosity and erythrocyte sedimentation rate before treatment had no statistical difference between the two groups(P>0.05),which were significantly improved after treatment(P<0.05),the inter-group difference had no statistical significance(P< 0.05);in the phar-macoeconomic analysis,the cost-effectiveness ratio and price sensitivity in the study group were significantly better than those in the control group(P<0.05).Conclusion Using pantoprazole in the treatment of ulcer bleeding has the effect close to rabeprazole.In clinical application process,it is needed to combine with the pa-tient′s condition,comprehensively consider the pharmacoeconomic factors,scientifically select the medication scheme for controlling the treatment cost on the basis for ensuring the curative effect.关键词
雷贝拉唑/泮托拉唑/消化性溃疡/出血/成本-效果分析Key words
rabeprazole/pantoprazole/peptic ulcer/bleeding/cost effectiveness analysis分类
医药卫生
