兰州大学学报（医学版）2018，Vol.44Issue(1)：74-77,82,5.DOI:10.13885/j.issn.1000-2812.2018.01.014
兰州市城关区社区人群甲状腺功能异常流行病学调查
Data analysis of thyroid dysfunction in community populations in Chengguan District of Lanzhou
摘要
Abstract
Objective To investigate the prevalence and influencing factors of thyroid dysfunction in community residents in Chengguan District of Lanzhou.Methods According to the principle of stratified cluster random sampling,587 eligible persons were included in the study,the subjects were investigated via questionnaire and the thyroid function was measured.Results The prevalence of previous thyroid dysfunction was 2.04％,and the rate of female patients was significantly higher than that of male (P ＜ 0.05),with their prevalence being 20.95％,mainly in subclinical hypothyroidism (92.68％);there is a significant difference (P ＜ 0.05) in thyroid dysfunction between men and women.With the increase of age,the prevalence of thyroid dysfunction gradually increased and there was a statistically significant difference (P ＜ 0.01).Age growth and smoking were important factors affecting thyroid function (P ＜ 0.01).(2) The expression of thyroid peroxidase antibody (TPOAb) was higher in women than in men (P ＜ 0.01),and there was no difference between different ages (P ＞ 0.05).The expression of TPOAb was also positively correlated with the levels of thyroid stimulating hormone (TSH)(P=0.014).Conclusion The prevalence of thyroid dysfunction is high in Lanzhou area,and prevention and treatment should be carried out actively.Attention should be paid to the screening and intervention of subclinical hypothyroidism patients.Elderly women are high risk groups,and focus should be laid on protecting the crowd in the course of scientific prevention and treatment of thyroid dysfunction.关键词
甲状腺功能/甲状腺过氧化物酶抗体/促甲状腺激素Key words
thyroid function/thyroid peroxidase antibody/thyroid stimulating hormone分类
医药卫生引用本文复制引用
曹冲,牛强龙,杨芳,李玉娟,乌丹,郭慧萍,王斌莉,宋佩,滕卫平,单忠艳,傅松波,汤旭磊,刘靖芳,马丽华,孙蔚明,牛滢,井高静,赵楠..兰州市城关区社区人群甲状腺功能异常流行病学调查[J].兰州大学学报（医学版）,2018,44(1):74-77,82,5.基金项目
国家卫计委公益性行业科研专项(201402005) （201402005）
兰州市城关区科技计划项目(2014-7-4) （2014-7-4）
兰州大学2017年大学生创新创业项目(20171073001237) （20171073001237）
