临床肝胆病杂志2018，Vol.34Issue(3)：579-582,4.DOI:10.3969/j.issn.1001-5256.2018.03.026
Viatorr支架与双支架技术行经颈静脉肝内门体分流术的临床疗效观察
Clinical effect of Viatorr stent versus double-stent technique in transjugular intrahepatic portosystemic shunt
摘要
Abstract
Objective To investigate the clinical effect of Viatorr stent versus double-stent technique in transjugular intrahepatic portosys-temic shunt(TIPS). Methods A total of 62 patients with portal hypertension who underwent TIPS in Department of Interventional Radiolo-gy,The First Affiliated Hospital of Anhui Medical University,from May 2015 to December 2016 were enrolled,among whom 55 had a major symptom of upper gastrointestinal bleeding and 7 had intractable ascites. According to the type of covered stent used in the surgery,the pa-tients were divided into Viatorr stent group with 22 patients and double-stent group with 40 patients(bare stent+Fluency covered stent). The patients were followed for 6-17 months after surgery,and the shunt patency rate,incidence rate of hepatic encephalopathy,and mortal-ity rate were determined. The independent samples t-test or the paired samples t-test was used for comparison of continuous data between groups,and the chi-square test was used for comparison of categorical data between groups. Results All patients underwent TIPS success-fully,and a total of 22 Viatorr stents,40 bare stents,and 40 Fluency covered stents,with a diameter of 8 mm,were implanted. Portal ve-nous pressure was significantly reduced from 28.7 ± 4.9 mm Hg before surgery to 18.7 ± 4.7 mm Hg after surgery in the Viatorr stent group (t=9.9,P<0.01)and from 27.2 ± 4.3 mm Hg before surgery to 18.8 ± 3.9 mm Hg after surgery in the double-stent group(t=13.5, P<0.01). Gastrointestinal bleeding was stopped for all 55 patients with upper gastrointestinal bleeding,and 7 patients with intractable asci-tes achieved ascites regression. The patency rate was 95.5% in the Viatorr stent group and 90.0% in the double-stent group,the inci-dence rate of hepatic encephalopathy was 9% in the Viatorr stent group and 15% in the double-stent group,and the mortality rate was 4.5% in the Viatorr stent group and 12.5% in the double-stent group;there were no significant differences between the two groups(all P>0.05). Conclusion Both Viatorr stent and double-stent technique have a good clinical effect in TIPS,and the short-term outcome of TIPS shunt established by Viatorr stent is similar to that of TIPS shunt established by double-stent technique. Further studies are needed to investigate the advantages of Viatorr stent over double-stent technique.关键词
高血压,门静脉/门体分流术,经颈静脉肝内/Viatorr覆膜支架/治疗结果Key words
hypertension,portal/portasystemic shunt/transjugular intrahepatic/Viatorr stent graft/treatment outcome分类
医药卫生引用本文复制引用
丁智锋,殷世武,张国兵,汪名权,潘升权..Viatorr支架与双支架技术行经颈静脉肝内门体分流术的临床疗效观察[J].临床肝胆病杂志,2018,34(3):579-582,4.基金项目
合肥市科技局基金(YW201512010005) （YW201512010005）
