临床肝胆病杂志2018，Vol.34Issue(3)：618-622,5.DOI:10.3969/j.issn.1001-5256.2018.03.040
血清标志物与瞬时弹性成像技术评估肝纤维化的研究进展
Research advances in serum markers and transient elastography in the evaluation of liver fibrosis
摘要
Abstract
Studies have shown that liver fibrosis and some cases of early liver cirrhosis can be reversed,and thus a timely,accurate judg-ment of fibrosis degree has important clinical significance in prevention/treatment and prognostic evaluation of chronic liver diseases. In re-cent years,great achievements have been made in the application of serum markers and transient elastography for the evaluation of liver fibro-sis. This article introduces the value of serological markers and related models in evaluating liver fibrosis,including CHI3L1,GP model, Forns,APRI,and FIB-4 index,and reviews the advances in the application of transient elastography in determining fibrosis stage in pa-tients with chronic liver diseases. It is pointed out that a combination of these two methods has a high value in evaluating fibrosis degree.关键词
肝硬化/弹性成像技术/生物学标记/诊断/综述Key words
liver cirrhosis/elasticity imaging techniques/biological markers/diagnosis/review分类
医药卫生引用本文复制引用
许峰铭,盛庆寿..血清标志物与瞬时弹性成像技术评估肝纤维化的研究进展[J].临床肝胆病杂志,2018,34(3):618-622,5.基金项目
国家"十二五"科技重大专项(2014ZX10005001) （2014ZX10005001）
广西科技厅课题(GZZX15-19) （GZZX15-19）
