临床肝胆病杂志2018，Vol.34Issue(3)：623-626,4.DOI:10.3969/j.issn.1001-5256.2018.03.041
酒精性肝纤维化的血清标志物研究进展
Research advances in serum markers for alcoholic liver fibrosis ZHANG Yanfang,HUANG Jing.
张艳芳 1黄晶1
作者信息
- 1. 吉林大学白求恩第一医院检验科,长春130021
- 折叠
摘要
Abstract
Alcoholic liver fibrosis is a series of pathological changes caused by excessive intrahepatic deposition of fibrous connective tissue due to hepatocyte inflammation and necrosis caused by excessive drinking. Laboratory markers help with the differentiation of alcoholic liver disease,and a combination of these markers and examination of liver fibrosis can be used for the diagnosis of alcoholic liver fibrosis. Liver biopsy remains the gold standard for the diagnosis of liver fibrosis,but its clinical application is limited by its invasiveness. Therefore,more and more new serum molecular markers with a diagnostic value have been identified in recent years,and great breakthroughs have been made. In addition,a noninvasive diagnostic and predictive model based on various biochemical parameters and imaging findings also brings new hope to the diagnosis and treatment of liver fibrosis. This article reviews the recent research advances in the noninvasive diagnosis of al-coholic liver fibrosis by serum markers.关键词
肝硬化,酒精性/生物学标记/综述Key words
liver cirrhosis/alcoholic,biological markers/review分类
医药卫生引用本文复制引用
张艳芳,黄晶..酒精性肝纤维化的血清标志物研究进展[J].临床肝胆病杂志,2018,34(3):623-626,4.
