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非侵袭性远端肢体缺血后适应对后循环缺血功能恢复的影响

阚培林 王玉 李晓燕 孙静 杨小娟 张晓霏 陈艳 胡彦红 申晓琳 杨海燕

临床神经病学杂志2018,Vol.31Issue(1):19-22,4.
临床神经病学杂志2018,Vol.31Issue(1):19-22,4.

非侵袭性远端肢体缺血后适应对后循环缺血功能恢复的影响

Effects of non-invasive remote limb ischemic postconditioning on the neurological function recovery of posterior circulation ischemia

阚培林 1王玉 2李晓燕 1孙静 1杨小娟 1张晓霏 1陈艳 1胡彦红 1申晓琳 1杨海燕1

作者信息

  • 1. 841000 新疆生产建设兵团第二师库尔勒医院神经内科
  • 2. 安徽医科大学第一附属医院神经内科
  • 折叠

摘要

Abstract

Objective To explore the effects of non-invasive remote limb ischemic postconditioning(NRLIP) on the neurological function recovery of posterior circulation ischemia(PCI).Methods One hundred and sixty PCI patients with vertigo were randomly divided into NRLIP group(80 cases)and control group(80 cases).All the patients accepted regular treatment and NRLIP group patients treated with NRLIP besides regular treatment.European evaluation of vertigo(EEV)scale was employed to assess the neurological function at the time of admission and at 7 d after admission.And the levels of serum high sensitivity C-reactive protein(hs-CRP), fibrinogen(FIB), D-dipolymer(D-D)and fasting plasma glucose(FPG)were measured.Results EEV value and the levels of hs-CRP, D-D and FIB in NRLIP group at 7 d after treatment were significantly decreased than those at admission(all P<0.05),and there was no statistical significance in FPG level(P>0.05).EEV value in control group at 7 d after treatment were significantly decreased than that at admission(P<0.01),there was no statistical significance in hs-CRP, D-D,FIB,FPG levels(all P>0.05).EEV value and the levels of hs-CRP,D-D,FIB and FPG at admission had no statistical significance between NRLIP group and control group(all P>0.05).Compared with control group, hs-CRP level in NRLIP group at 7 d after treatment was significantly decreased(P<0.01), the difference value of EEV and FIB in NRLIP group were significantly increased(all P<0.01),and D-D level,hs-CRP level,FIB level and FPG level and difference value of D-D and FPG had no statistical significance(all P>0.05).No obvious adverse effect was observed on all patients.Conclusion NRLIP has a facilitating effect on the neurological functional recovery of PCI.

关键词

脑血管疾病/后循环缺血/非侵袭性远端肢体缺血/缺血后适应

Key words

cerebral vascular disease/posterior circulation ischemia/non-invasive distal limb ischemic postconditioning/ischemic postconditioning

分类

医药卫生

引用本文复制引用

阚培林,王玉,李晓燕,孙静,杨小娟,张晓霏,陈艳,胡彦红,申晓琳,杨海燕..非侵袭性远端肢体缺血后适应对后循环缺血功能恢复的影响[J].临床神经病学杂志,2018,31(1):19-22,4.

临床神经病学杂志

OACSTPCD

1004-1648

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