农药学学报2018，Vol.20Issue(1)：49-57,9.DOI:10.16801/j.issn.1008-7303.2018.0012
4种苦参碱制品对非靶标生物的毒性评价
Toxicity evaluation of 4 matrine-based products on non-target organisms
摘要
Abstract
Environmental safety assessment of non-tartarget organisms is essential for the development and application of new pesticides. In order to guide the rational use of matrine-based botanical pesticide products, the toxicities of 4 matrine-based products (matrine, total alkaloid, mtrine extract and 0.3％matrine AS) on 6 kinds of non-target organism and the effect of succeeding crop (cowpea) were investigated and compared. The results indicated that the acute toxicities of matrine, total alkaloid, mtrine extract and 0.3％ matrine AS were low for quail, silkworm, bee, earthworm, tadpole and zebra fish. And these products were also low risk to cowpea. 0.3％ Matrine AS has no chronic toxicity to the silkworm. But there were significant differences among toxicities of different products on the samespecies.The7 d-LD50 value of matrine, total alkaloid, mtrine extract and 0.3％ matrine AS were 512, 504, >1000 and >3000 mg a.i./kgquail on quail, respectively; >3000, 1300, >5000 and 821 mg a.i./L on silkworm (96 h-LC50), respectively; 1145, 1361, >3000 and 337 mg a.i./L on bee(48 h-LC50), respectively; 549, 428, 564 and >1000 mg a.i./kgsoil on earthworm(14 d-LC50), respectively; >100,>100, 263 and 15 mg a.i./L on tadpole(48 h-LC50), respectively; and 85, 65, 193 and 20 mg a.i./L on zebra fish(96 h-LC50), respectively. Among 4 products, mtrine extract had the lowest toxicity. Thus, matrine-based products are safe to non-target organisms, and will exhibit good ecological benefits in field application.关键词
苦参碱/非靶标生物/植物源农药/毒性/安全性评价Key words
matrine/non-target organisms/botanical pesticide/toxicity/safety evaluation分类
资源环境引用本文复制引用
豆敏详,史晓玲,马志卿,张兴,吴志凤..4种苦参碱制品对非靶标生物的毒性评价[J].农药学学报,2018,20(1):49-57,9.基金项目
绿色杀菌抗病毒剂及害虫生物防治剂创制开发(2014BAD23B01). （2014BAD23B01）
