四川医学2017，Vol.38Issue(12)：1420-1423,4.DOI:10.16252/j.cnki.issn1004-0501-2017.12.018
新生儿肺炎克雷伯菌败血症临床特点和药敏分析
Clinical Characteristicsand Drug Sensitivity Analysis of Neonatal Septicemia Caused by Klebsiella Pneumoniae
杜逸亭 1胡旭红 1杨晓荣 1王译 1徐若梅2
作者信息
- 1. 成都市妇女儿童中心医院新生儿科,四川成都610091
- 2. 成都市新世纪妇女儿童医院新生儿科,四川成都610015
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and drug sensitivity of neonatal septicemia caused by Klebsiella pneumoniae(KP),and to provide the basis for clinical rational treatment.Methods The clinical data and antimicrobial susceptibility of 49 neonates with septicemia caused by Klebsiella pneumoniae were retrospectively analyzed.Results Among the 49 strains of Klebsiella pneumoniae,30 strains(61.22％)produced extended spectrum beta lactamases (ESBLs)and 19 strains (38.78％)were non ESBLs-producing strains(ESBLs).Klebsiella pneumoniae was not sensitive to most penicillins and cephalo sporins drug but the sensitivity rate to amikacin and meropenem reached 100％.Conclusion Klebsiella pneumoniae septicemia is mostly hospital infection partly caused by ESBLs-producing strains,which have strong drug resistance and are not sensitive to commonly used antibiotics.Antibiotics should be used according to the results of drug sensitivity test in order to improve the clinical cure rate.关键词
新生儿/败血症/肺炎克雷伯茵/超广谱β-内酰胺酶Key words
neonates/septicemia/klebsiella pneumoniae/extended spectrum beta lactamases分类
医药卫生引用本文复制引用
杜逸亭,胡旭红,杨晓荣,王译,徐若梅..新生儿肺炎克雷伯菌败血症临床特点和药敏分析[J].四川医学,2017,38(12):1420-1423,4.
