三峡大学学报(自然科学版)2018,Vol.40Issue(2):90-94,5.DOI:10.13393/j.cnki.issn.1672-948X.2018.02.018
3D打印工艺参数对组织工程支架微观结构的影响研究
Effect of 3D Printing Parameters on Microstructure of Tissue Engineering Scaffolds
摘要
Abstract
Extrusion-based 3D printing is one of the most important techniques for preparing tissue engineer-ing scaffolds.A well-performed tissue engineering scaffold must have an internal microstructure with small pores and high porosity.A thermo-mechanical coupling dynamics model of printing material forming process is established for the scaffold forming dynamic process in extrusion-based 3D printing.The influence of the main parameters in printing process on the pore size and remelting properties of the formed scaffold is studied by numerical simulation.The results show that the pore size of the scaffold increases with both the printing time interval and material viscosity increasing,but with the substrate temperature decreasing while the re-sults of the remelting degree of the scaffold is competely opposite;and the change of material viscosity has the most obvious influence on the pore size and remelting degree of the scaffold formed.关键词
3D打印/组织工程支架/孔隙尺寸/重熔度Key words
3D printing/tissue engineering scaffolds/pore size/remelting degree分类
机械制造引用本文复制引用
陈从平,冉艳华,胡琼,吕添..3D打印工艺参数对组织工程支架微观结构的影响研究[J].三峡大学学报(自然科学版),2018,40(2):90-94,5.基金项目
国家自然科学基金(51475266,51005134) (51475266,51005134)