烟草科技2018,Vol.51Issue(2):87-94,8.
基于第三代测序技术的基因组组装方法及其在烟草中的应用
Genome assembly based on the third-generation sequencing technology and its application in tobacco
摘要
Abstract
The third-generation sequencing technology has been widely used in genome research due to its advantage of long-fragment reads. The development of the sequencing technology was reviewed and the advantages and disadvantages of three different generations of sequencing technologies were summarized. Based on the third-generation sequencing, the methods of genome assembly including data pre-processing, sequence assembly, sequence repairing after assembly and chromosome localization methods were tracked and statistically analyzed. Application of sequencing technology and genome assembly in tobacco genome research was introduced.关键词
第三代测序/基因组/组装/烟草Key words
Third-generation sequencing/Genome/Assembly/Tobacco分类
生物科学引用本文复制引用
卢鹏,金静静,李泽锋,曹培健,范楷,许亚龙..基于第三代测序技术的基因组组装方法及其在烟草中的应用[J].烟草科技,2018,51(2):87-94,8.基金项目
中国烟草总公司郑州烟草研究院院长科技发展基金项目"利用三代测序数据填补基因组缺失序列的方法研究"(902016CA0170). (902016CA0170)