中国医疗设备2018，Vol.33Issue(3)：31-35,69,6.DOI:10.3969/j.issn.1674-1633.2018.03.008
智能放射吸收法的临床应用——人体手臂骨骨密度的测量及其骨质疏松的评估
Clinical Application of Intelligent Radiographic Absorptiometry–Human Forearm's Bone Mineral Measurements and the Osteoporosis Assessments
陈建锋 1范运洲 2李鹏 2黄松正2
作者信息
- 1. 西北大学医学院 放射科,美国 伊利诺州 芝加哥 60611
- 2. 浙江康源医疗器械有限公司 研发部,浙江 杭州 310051
- 折叠
摘要
Abstract
Objective In this paper, a bone mineral measurement method called intelligent radiographic absorptiometry (i-RA) was described and the measurement results were presented. Methods Firstly, digital radiography (DR) images were acquired from 228 human volunteers'forearms in vivo,then the i-RA method was used to process these DR images,the algorithm automatically placed the region of interest on the radius centered at 1/3 of the non-dominant forearm length measured from the styloid process on the ulna, both values of the bone mineral density (BMD) and T-score of these regions were determined. Results By comparing with the measurement results with using dual-energy X-ray absorptiometry (DXA), which had been widely used for BMD measurements and was defined as World Health Organization gold standard, the measurement results showed that the Pearson's correlation coefficients were 0.984 for BMD, and 0.979 for T-scores, and the ROC results showed that sensitivity was 98.5%, specificity was 98.2%, area under curve was 0.998. Conclusion DXA method can be potentially replaced by the i-RA method to measure human radius' BMD and T-scores, and to diagnose osteoporosis.关键词
智能放射吸收法/双能量X-射线吸收法/桡骨骨密度/T-值Key words
intelligent radiographic absorptiometry (i-RA)/dual-energy X-ray absorptiometry/radius bone mineral density (BMD)/T-score分类
医药卫生引用本文复制引用
陈建锋,范运洲,李鹏,黄松正..智能放射吸收法的临床应用——人体手臂骨骨密度的测量及其骨质疏松的评估[J].中国医疗设备,2018,33(3):31-35,69,6.
