中国感染控制杂志2018，Vol.17Issue(4)：299-303,5.DOI:10.3969/j.issn.1671-9638.2018.04.005
62株耐碳青霉烯类鲍曼不动杆菌的同源性分析
Homology analysis on 62 strains of carbapenem-resistant Acinetobacter baumannii
摘要
Abstract
Objective To understand the homology of carbapenem-resistant Acinetobacter baumannii(CRAB)iso-lated from hospitalized patients in a hospital,and provide evidence for the prevention of CRAB spread in hospital. Methods Antimicrobial susceptibility testing of 62 strains of CRAB isolated from all kinds of clinical specimens from hospitalized patients between August 2015 and November 2016 was performed,homology and epidemic charac-teristics were analyzed by pulsed-field gel electrophoresis(PFGE).Results 62 strains of CRAB were mainly from sputum specimens(88.71%),all were resistant to ceftazidime,cefepime,imipenem,meropenem,and ciprofloxa-cin,resistance rate to levofloxacin was the lowest(25.81%). 62 strains of CRAB were divided into 14 different types(A-N),type B,D,E,J,and M only contained 1 strain respectively,type F contained 5 subtypes,type A,G,H,and K had 3 subtypes respectively,type C and I had 2 subtypes respectively.Clinical data of the main cloned strains were analyzed,32 strains(51.61%)were isolated from patients in intensive care unit(ICU),and 12 strains (19.35%)from patients who had ever stayed in ICU.Conclusion There are two forms of Acinetobacter baumannii prevailed in hospital,which are external and internal spread,infection control should be strengthened.关键词
鲍曼不动杆菌/耐碳青霉烯类抗生素/脉冲场凝胶电泳/PFGE/同源性Key words
Acinetobacter baumannii/carbapenem/pulsed-field gel electrophoresis/PFGE/homology分类
医药卫生引用本文复制引用
何磊,邱景富..62株耐碳青霉烯类鲍曼不动杆菌的同源性分析[J].中国感染控制杂志,2018,17(4):299-303,5.基金项目
重庆市卫生计生委重点项目(20141024) （20141024）
