中国免疫学杂志2018,Vol.34Issue(3):478-480,封3,4.DOI:10.3969/j.issn.1000-484X.2018.03.033
IL-36在炎性疾病中的研究进展
IL-36 in inflammatory diseases
摘要
Abstract
The IL-36,which is a member of IL-1 family,consists of three ligands IL-36α,IL-36β and IL-36γ. The cytokines exert their proinflammatory effects through a specific IL-36 receptor(IL-36R),IL-36Ra is an antagonist of IL-36R.IL-36 acts as a helper,involved in dendritic cell and T cell activation, maturation, polarization, antigen presentation and stimulating inflammatory factor production,and so on.IL-36,as a new proinflammatory factor,plays a very important role in many inflammation diseases, including psoriasis,inflammatory bowel disease,arthritis,SLE,lung diseases and so on.关键词
白介素36/免疫效应/炎性疾病Key words
IL-36 family cytokines/Immune function/Inflammatory diseases分类
医药卫生引用本文复制引用
李妹,崔天盆..IL-36在炎性疾病中的研究进展[J].中国免疫学杂志,2018,34(3):478-480,封3,4.基金项目
本文为武汉市黄鹤英才计划(No.201260523191-3). (No.201260523191-3)