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先天性白内障Rncat小鼠行为学检测与分析

张燕 王莹 马嵋 燕顺生 陈欣如

中国比较医学杂志2018,Vol.28Issue(3):28-31,4.
中国比较医学杂志2018,Vol.28Issue(3):28-31,4.DOI:10.3969/j.issn.1671-7856.2018.03.005

先天性白内障Rncat小鼠行为学检测与分析

Measurement and analysis of the behavioral changes of Rncat congenital cataract mice

张燕 1王莹 1马嵋 2燕顺生 1陈欣如1

作者信息

  • 1. 新疆维吾尔自治区疾病预防控制中心,乌鲁木齐 830002
  • 2. 新疆医科大学第一附属医院人类疾病动物模型研究实验室,乌鲁木齐 830054
  • 折叠

摘要

Abstract

Objective To measure and analyze the behavioral changes of Rncat congenital cataract mice. Methods Normal BALB/c mice and KM mice were used as control group,and inbred and random mated Rncat congenital cataract mice were used as experimental group. Behavioral tests, including the open field test, coat-hanger test, forced swimming test,and tail suspension test,were conducted on the mice. Results Compared with the inbred Rncat congenital cataract mice,the residence time in the open field test,the immobility time in the forced swimming test and tail suspension test of the BALB/c mice, randomly-mated Rncat congenital cataract mice and KM mice were significantly different. Conclusions There are certain differences in behavioral performance between the Rncat congenital cataract mice and the other mice. Our findings may provide a useful reference for future researchers.

关键词

先天性白内障Rncat小鼠/旷场实验/衣架实验/强迫游泳实验/悬尾实验

Key words

Rncat congenital cataract mice/open field test/coat-hanger test/forced swimming test/tail suspension test

分类

医药卫生

引用本文复制引用

张燕,王莹,马嵋,燕顺生,陈欣如..先天性白内障Rncat小鼠行为学检测与分析[J].中国比较医学杂志,2018,28(3):28-31,4.

基金项目

新疆维吾尔自治区自然科学基金资助项目(编号:2016D01A066). (编号:2016D01A066)

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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