中国比较医学杂志2018，Vol.28Issue(3)：98-102,5.DOI:10.3969/j.issn.1671-7856.2018.03.019
近红外荧光(NIRF)染料在肿瘤诊断中的应用
Application of near-infrared fluorescent dyes in tumor diagnosis
摘要
Abstract
Optical molecular imaging is more and more widely used in the field of biomedical sciences due to its advantageous properties such as non-invasive, real-time and high resolution. As a kind of important optical molecular imaging probe,the near-infrared fluorescent(NIRF)dyes exhibit less tissue absorption and strong tissue penetration,and has been gradually applied to the early diagnosis of tumors. Researchers have developed a number of NIRF dyes with high potential for clinical application by conjugating tumor-targeting ligands,nano-modifications and multimodal NIRF imaging, and have significantly improved the specificity and sensitivity of these NIRF dyes in tumor diagnosis. In this paper we provide a review on the application of NIRF dyes in tumor diagnosis.关键词
近红外荧光染料/肿瘤/诊断/纳米修饰/多模态成像Key words
near-infrared fluorescent dye/NIRF dye/tumors/diagnosis/nano-modifications/multimodal imaging分类
医药卫生引用本文复制引用
赵勇,王浩,师长宏..近红外荧光(NIRF)染料在肿瘤诊断中的应用[J].中国比较医学杂志,2018,28(3):98-102,5.基金项目
国家自然科学基金(编号:31572340,31772546) （编号:31572340,31772546）
军队实验动物专项(编号:SYDW2016-006). （编号:SYDW2016-006）
