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急性肾损伤与早期诊断生物标志物

李艳红 方芳

中国实用儿科杂志2018,Vol.33Issue(2):109-113,5.
中国实用儿科杂志2018,Vol.33Issue(2):109-113,5.DOI:10.19538/j.ek2018020607

急性肾损伤与早期诊断生物标志物

Acute kidney injury and biomarkers for early diagnosis

李艳红 1方芳2

作者信息

  • 1. 苏州大学附属儿童医院肾内科,江苏苏州215025
  • 2. 苏州大学儿科临床研究院,江苏苏州215025
  • 折叠

摘要

Abstract

Acute kidney injury(AKI) is a common syndrome.Serum creatinine and urine output are the most commonly used in clinical evaluation of kidney injury,but they are poor markers for early diagnosis of AKI,which results in delayed treatment and high mortality.Research in AKI has focused on identifying biomarkers for early detection.Since AKI in children and adults is not the same,investigation is needed to explore the role of potential biomarkers for prediction of AKI in pediatric cohorts.This review serves to update the topic of promising AKI biomarkers and focuses on pediatric biomarker's advantages and limitations to improve early detection in children.

关键词

急性肾损伤/生物标志物/早期诊断/预测价值

Key words

acute kidney injury/biomarkers/early diagnosis/predictive value

分类

医药卫生

引用本文复制引用

李艳红,方芳..急性肾损伤与早期诊断生物标志物[J].中国实用儿科杂志,2018,33(2):109-113,5.

基金项目

国家自然科学基金(81370773,81501840) (81370773,81501840)

江苏省社会发展面上项目(BE2016675) (BE2016675)

江苏省自然科学基金(BK20171217) (BK20171217)

苏州市临床重点病种诊疗技术专项(LCZX201611) (LCZX201611)

中国实用儿科杂志

OA北大核心CSCDCSTPCD

1005-2224

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