中国实用儿科杂志2018,Vol.33Issue(2):109-113,5.DOI:10.19538/j.ek2018020607
急性肾损伤与早期诊断生物标志物
Acute kidney injury and biomarkers for early diagnosis
摘要
Abstract
Acute kidney injury(AKI) is a common syndrome.Serum creatinine and urine output are the most commonly used in clinical evaluation of kidney injury,but they are poor markers for early diagnosis of AKI,which results in delayed treatment and high mortality.Research in AKI has focused on identifying biomarkers for early detection.Since AKI in children and adults is not the same,investigation is needed to explore the role of potential biomarkers for prediction of AKI in pediatric cohorts.This review serves to update the topic of promising AKI biomarkers and focuses on pediatric biomarker's advantages and limitations to improve early detection in children.关键词
急性肾损伤/生物标志物/早期诊断/预测价值Key words
acute kidney injury/biomarkers/early diagnosis/predictive value分类
医药卫生引用本文复制引用
李艳红,方芳..急性肾损伤与早期诊断生物标志物[J].中国实用儿科杂志,2018,33(2):109-113,5.基金项目
国家自然科学基金(81370773,81501840) (81370773,81501840)
江苏省社会发展面上项目(BE2016675) (BE2016675)
江苏省自然科学基金(BK20171217) (BK20171217)
苏州市临床重点病种诊疗技术专项(LCZX201611) (LCZX201611)