中国药科大学学报2018，Vol.49Issue(1)：87-92,6.DOI:10.11665/j.issn.1000 -5048.20180112
石墨烯量子点荧光猝灭-恢复法测定Cu2+与谷胱甘肽的含量
Detection of copper ions and glutathione based on off-on fluorescent gra-phene quantum dots
摘要
Abstract
We developed a rapid method to detect Cu2+and glutathione(GSH)based on the fluorescence quenching-recovery properties of graphene quantum dots(GQDs),which were synthesized by the gentle oxidation of graphite powder.The results revealed that the fluorescence intensity of GQDs versus concentration of Cu2+and GSH had good linearity, with the detection limits of 0.01 and 0.1 mmol/L, respectively.The fluorescence quenching was linearly proportional to the concentrations of Cu2+ranging from 1.0 to 10.0 mmol/L;the fluores-cence intensity was linearly enhanced with the concentrations of GSH ranging from 0.1 to 1.0 mmol/L.In addi-tion,the method was successfully applied to the determination of real samples with recoveries falling between 93％-101％ and 96％-107％,respectively.This method is simple,accurate and precise.There was no interference with other familiar co-existing metal ions and potential materials.关键词
石墨烯量子点/Cu2+谷胱甘肽/荧光猝灭-恢复/含量测定Key words
graphene quantum dots/Cu2+/glutathione/fluorescence quenching-recovery/content determination分类
医药卫生引用本文复制引用
宋凤娟,艾永玲,钟文英,王菁..石墨烯量子点荧光猝灭-恢复法测定Cu2+与谷胱甘肽的含量[J].中国药科大学学报,2018,49(1):87-92,6.基金项目
国家自然科学基金资助项目(No.21405178) （No.21405178）
江苏省自然科学基金资助项目(No.BK20161455) （No.BK20161455）
中央高校基本科研业务费专项基金资助项目(No.2016ZZD004) （No.2016ZZD004）
中国药科大学医药生物功能材料重点实验室开放基金资助项目This work was supported by the National Natural Science Foundation of China ( No. 21405178) （ No. 21405178）
the Natural Science Foundation of Jiangsu Province ( No. BK20161455) （ No. BK20161455）
the Fundamental Research Funds for the Central Universities ( No. 2016ZZD004) and the Open Project Fund of Key Laboratory of Biomedical Functional Materials of China Pharmaceutical University （ No. 2016ZZD004）
