中国卒中杂志2018，Vol.13Issue(2)：106-113,8.DOI:10.3969/j.issn.1673-5765.2018.02.003
院前通知对急性颅内大动脉闭塞患者取栓流程及疗效的影响
The Impact of Prehospital Notification on Door-to-reperfusion Time and Clinical Outcome after Thrombectomy
摘要
Abstract
Objective To investigate the impact of prehospital notification (PN) on the door-to-reperfusion time (DRT) and outcome of patients who underwent thrombectomy. Methods A retrospective analysis was made upon clinical and imaging data of patients who underwent thrombectomy in Zhejiang Provincial People's Hospital from January 2015 to December 2016. PN was defined as a local hospital informing our stroke team prior to the transfer of thrombectomy candidates. The baseline characteristics, DRT and outcome between patients with and without PN were compared. Good outcome was defined as modified Rankin Scale score ≤3 at 3 months. Results A total of 123 patients underwent thrombectomy were enrolled, including 57 (46.3%) patients that was identified as PN group. Among patients who achieved reperfusion after thrombectomy (n=100), the DRT of PN group was significantly shorter than that of non-PN group (P<0.001). Implementing intravenous thrombolysis before thrombectomy [odds ratio (OR)=2.774, P=0.023] was an independent factor for good outcome,while PN was not(OR=2.586,P=0.058).Nevertheless,PN combined with preoperative intravenous thrombolysis was an independent factor for good outcome (OR=7.662, P=0.006).Conclusion PN can shorten DRT. Patients who achieved reperfusion after thrombectomy could benefit from preoperative intravenous thrombolysis. PN combined with preoperative intravenous thrombolysis would increase the beneficial rate by 2.7 times.关键词
血管内治疗/院前通知/急救网络/时间管理/预后Key words
Endovascular therapy/Prehospital notification/Emergency network/Time management/Outcome引用本文复制引用
张圣,史宗杰,王振,刘芳,陈波,张凝远,徐天波,耿昱..院前通知对急性颅内大动脉闭塞患者取栓流程及疗效的影响[J].中国卒中杂志,2018,13(2):106-113,8.基金项目
浙江省科技厅2018年度重点研发计划项目(2018C03008)浙江省医药卫生科技项目(平台项目)(2018274810,2018274161)浙江省中医药科学研究基金项目(2015ZB009) （2018C03008）
