中华肝脏外科手术学电子杂志2018，Vol.7Issue(1)：53-56,4.DOI:10.3877/cma.j.issn.2095-3232.2018.01.014
增强CT及增强MRI图像融合技术在原发性肝癌治疗决策中的价值
Value of enhanced CT and enhanced MRI image fusion in treatment decisions for primary liver cancer
摘要
Abstract
Objective To explore the effect of enhanced CT and enhanced MRI image fusion technique in making treatment decisions for primary liver cancer (PLC). Methods Clinical data of 55 patients with PLC who were treated in the Third Affiliated Hospital of Sun Yat-sen University between January 2013 and January 2015 were analyzed retrospectively. There were 42 males and 13 females, aged from 18-84 and with a median age of 52 years old. The informed consents of all patients were obtained and the local ethical committee approval was received. All the patients underwent enhanced CT and gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) enhanced MRI. CT and MRI images were fused by using flexible registration method based on finite element. Treatment decisions for these patients were discussed and made by HCC multidisciplinary consultation group. Discussion was conducted twice for each patient. The first discussion was based on enhanced CT images and the second was based on fused images. Changes of treatment decisions were observed and analyzed. Results Treatment decisions based on enhanced CT images included radical treatment in 8 cases, palliative surgical treatment in 35 cases and systemic medicine treatment in 12 cases. Treatment decisions based on fused images included radical treatment in 4 cases, palliative surgical treatment in 36 cases and systemic medicine treatment in 15 cases. Compared with those based on enhanced CT images, the conversion rate of radical treatment, palliative surgical treatment and systemic medicine treatment based on fused images was respectively 50%(4/8), 3%(1/35) and 25%(3/12). Conclusions Enhanced CT and Gd-EOB-DTPA enhanced MRI image fusion can change the treatment decisions for some patients with HCC, and it is of certain significance in optimizing the treatment protocols.关键词
肝肿瘤/体层摄影术/磁共振成像/钆塞酸二钠/图像融合Key words
Liver neoplasms/Tomography/Magnetic resonance imaging/Gadolinium ethoxybenzyl diethyle-netriaminepentaacetic acid/Image fushion引用本文复制引用
唐建信,吴祥元,姜楠,李星,邢艳芳,刘尚鑫,吴晨飞,江文钊,陈明,莫嘉辉,吴伟坤..增强CT及增强MRI图像融合技术在原发性肝癌治疗决策中的价值[J].中华肝脏外科手术学电子杂志,2018,7(1):53-56,4.基金项目
国家自然科学基金(81572368) （81572368）
广东省自然科学基金(2016A030313278,2016A030313302,2014A030313146) （2016A030313278,2016A030313302,2014A030313146）
广东省科技计划项目(2014A020212084) （2014A020212084）
