浙江医学2018，Vol.40Issue(1)：43-46,4.DOI:10.12056/j.issn.1006-2785.2017.40.1.2017-707
中性粒细胞CD64指数在婴幼儿社区获得性肺炎诊断中的应用价值
Value of nCD64 for diagnosis of community-acquired pneumonia in infants and young children
摘要
Abstract
Objective To assess the value of neutrophils nCD64 index for diagnosis of community-acquired pneumonia in infants and young children.Methods Infants and young children with community-acquired pneumonia were enrolled in the study,including 60 cases of bacterial infections,60 cases of mycoplasma infection;and 60 healthy young children and infants served as control group.The nCD64 index was measured by flow cytometry,the CRP and PCT were determined.There indexes were determined in bacterial infection group at 3 days after treatment.Results There were significant differences in CD64 index,CRP and PCT levels between bacterial pneumonia group and healthy controls,between bacterial pneumonia group and mycoplasma pneumonia group (P＜0.05).For bacterial pneumonia group,there were significant differences in CD64 index,CRP and PCT levels (P＜0.05) before and after treatment,nCD64 index was positively correlated with CRP.The sensitivities and specificities of nCD64 for diagnosis of bacterial pneumonia were 81.6％,respectively.Conclusion Determination of nCD64 index is of value in diagnosis of bacterial lung infection and evaluation of therapeutic effectiveness in infants and young children.关键词
nCD64指数/C反应蛋白/降钙素原/细菌性肺炎/支原体肺炎Key words
nCD64/C-reactive protein/Procalcitonin/Bacterial pneumonia/Mycoplasmal pneumonia引用本文复制引用
瞿斐,杨爱平,张群威,窦琳琳,刘军..中性粒细胞CD64指数在婴幼儿社区获得性肺炎诊断中的应用价值[J].浙江医学,2018,40(1):43-46,4.基金项目
杭州市社会和农业发展入库项目(20163501Y84),萧山科技局引导项目(2016303) （20163501Y84）
