摘要
Abstract
Objective To analyze the correlation of percutaneous oxygen pressure (PctO2) and percutaneous carbon dioxide pressure (PctCO2) with arterial blood gas indexes in neonatus with different microcirculation (MC) disturbance.Methods Ninety six critical neonates treated in NICU of Yongkang Maternal and Child Health Hospital from January 2016 to January 2017 were enrolled.According to the capillary refill time (CRT) patients were divided into normal MC group(n=36),mild MC disturbance group(n=30) and severe MC disturbance group(n=30).The percutaneous blood gas indexes PctO2,PctCO2 and the arterial blood gas indexes PaO2,PaCO2 were measured at the same time.The levels of PctO2 and PctCO2 were compared among the groups,the correlations between PctO2 and PaO2,between PctCO2 and PaCO2 were analyzed by Pearson analysis.The value of PctO2 and PctCO2 in assessing hypoxia and CO2 retention was analyzed by ROC curves.Results There were positive correlations between PctO2 and PaO2 (r=0.760,P＜0.01) and between PctCO2 and PaCO2 (r=0.589,P＜0.01) in children with normal MC.In children with mild or severe MC disturbance the PctCO2 was positively correlated with PaCO2 (r=0.728 and 0.698,both P＜0.01),but PctO2 was not correlated with PaO2 (r=0.316 and 0.141,both P ＞0.05).The AUC on evaluating hypoxia and CO2 retention by PctO2 and PctCO2 in the normal,mild and severe MC disturbance were 0.88 (P =0.012) and 0.65 (P =0.112),0.58(P=0.348) and 0.91 (P =0.001),0.62(P =0.152) and 0.89(P =0.008),respectively.Conclusion The percutaneous blood gas indexes PctO2 and PctCO2 can better replace arterial blood gas indexes PaO2 and PaCO2 in neonatus with normal MC.For neonatus with mild or severe MC disturbance PaCO2 is correlated with PaCO2,while PctO2 can't reflect the changes of PaO2 and arterial blood gas analysis is necessary.关键词
经皮二氧化碳分压/经皮氧分压/PaCO2/PaO2/微循环Key words
PctCO2/PctO2/PaCO2/PaO2/Microcirculation
