中山大学学报（医学科学版）2018，Vol.39Issue(2)：282-286,302,6.
胎儿脐动脉血流彩色多普勒在系统性红斑狼疮不良妊娠结局的预测作用
Predictive Value of Fetal Umbilical Artery Doppler on Adverse Pregnancy Outcomes in Women with Systemic Lupus Erythematosus
摘要
Abstract
[Objective]To explore the adverse pregnancy outcomes(APO)and examine the predictive value of umbil-ical artery Doppler in systemic lupus erythematosus(SLE)pregnancies.[Methods]Data of 273 pregnancies from 2010 to 2016 were analyzed retrospectively. Pulsatility index(PI),resistance index(RI),and systolic/diastolic ratio(S/D)of the umbilical artery flow velocity data were monitored by Doppler ultrasound.[Results]One or more APO occurred in 61.9% of patients with SLE,among which pregnancy loss occurred in 60 cases;preterm birth in 56 cases;intrauterine growth retardation occurred in 20 cases;and fetal distress occurred in 21 cases.Twelve of pregnancies resulted in neona-tal Lupus. In total,118 patients underwent fetal umbilical artery Doppler during 28~34 gestational weeks. Doppler PI, RI,and S/D were significantly higher in the APO groups than in the patients without APO.[Conclusion]Pregnancies in lupus still had an increased risk of APO.Umbilical artery Doppler was useful in predicting APO in lupus pregnancies.关键词
系统性红斑狼疮/不良妊娠结局/胎儿/脐动脉血流多普勒彩超声Key words
systemic lupus erythematosus/adverse pregnancy outcomes/fetal/umbilical artery Doppler分类
医药卫生引用本文复制引用
王晓东,王竹,田媛媛,赖雪恩,陈冬莹..胎儿脐动脉血流彩色多普勒在系统性红斑狼疮不良妊娠结局的预测作用[J].中山大学学报（医学科学版）,2018,39(2):282-286,302,6.基金项目
广东省科技计划项目(2016ZC0104) （2016ZC0104）
广州中医药大学青年科研人才培优项目(2016QN01) （2016QN01）
