中国现代中药2018，Vol.20Issue(2)：123-144,22.DOI:10.13313/j.issn.1673-4890.20170503001
阿魏属药用植物的物质基础
Bioactive Material Basis of Medicinal Plants in Genus Ferula
摘要
Abstract
Genus Ferula is taxonomically classified as a member of Umbelliferae and a genus of well over 150 species in global,13 of which are medicinal in China. In this article,studies on their chemical constituents and biological activities as well as clinical uses were reviewed. The monoterpenoid,sesquiterpenoid and coumarin compounds are predominantly dominant type not only in amount but also in structural varieties,which should be one of important bioactive material basis of medicinal plants in the genus Ferula. The most characteristic feature of many monoterpenoid or sesquiterpenoid compounds in genus Feru-la is embellished having the structural unit of coumarins. Many biological features of medicinal plants in this genus such as cy-totoxicity,antibacterial,antiviral,P-glycoprotein inhibitory and antiinflammatory activities have been attributed to monoter-pene-coumarin or sesquiterpene-coumarin. These results could be used for pharmaphylogenic research of the medicinal herbs in genus Ferula.关键词
阿魏属/生物活性物质基础/单萜杂合香豆素/倍半萜杂合香豆素Key words
Genus Ferula/bioactive material basis/monoterpene-coumarin/sesquiterpene-coumarin引用本文复制引用
杨秀伟..阿魏属药用植物的物质基础[J].中国现代中药,2018,20(2):123-144,22.基金项目
"十二五"国家科技支撑项目(2011BAI07B08) （2011BAI07B08）
