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黑果枸杞酚性成分研究

程礼芝 郭平霞 戴伟峰 晏永明 刘宝华 王淑美 程永现

中国现代中药2018,Vol.20Issue(2):159-162,178,5.
中国现代中药2018,Vol.20Issue(2):159-162,178,5.DOI:10.13313/j.issn.1673-4890.20170901006

黑果枸杞酚性成分研究

Phenolic Compounds from Lycium ruthenicum

程礼芝 1郭平霞 2戴伟峰 3晏永明 3刘宝华 2王淑美 4程永现1

作者信息

  • 1. 广东药科大学,广东 广州 510006
  • 2. 深圳大学医学部药学院,广东 深圳 518060
  • 3. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南 昆明 650201
  • 4. 深圳大学医学部生物化学与分子生物学系,广东 深圳 518060
  • 折叠

摘要

Abstract

Objective:To study phenolic compounds from the fruits of Lycium ruthenicum Murr.Methods:Compounds were isolated by using column chromatography and their structures were elucidated by spectroscopic methods.Results:Four-teen compounds isolated from L.ruthenicum were identified as ficusal(1),methyl 2-O-β-D-glucopyranosyl-2,4,6-trihydroxy-benzoate(2),esculetin(3),p-coumaric acid glucosyl ester(4),trans-ferulic acid(5),trans-caffeic acid(6),(E)-4-me-thoxycinnamic acid(7),4-hydroxycinnamate(8),dihydroferulic acid methyl ester(9),vanillic acid(10),protocatechuic acid(11),4-hydroxybenzoic acid(12),protocatechuic aldehyde(13),and(E)-but-2-enedioic acid monomethyl ester(14), respectively. Conclusion:Compounds 1-4,7,9,and 14 were isolated from the title species for the first time.In addition, the activities of compounds 1 and 2 towards SIRT1 and SIRT6 were tested.

关键词

黑果枸杞/酚性成分/SIRT1/SIRT6

Key words

Lycium ruthenicum/phenolic compounds/SIRT1/SIRT6

引用本文复制引用

程礼芝,郭平霞,戴伟峰,晏永明,刘宝华,王淑美,程永现..黑果枸杞酚性成分研究[J].中国现代中药,2018,20(2):159-162,178,5.

基金项目

国家杰出青年科学基金(81525026) (81525026)

中国现代中药

OACSTPCD

1673-4890

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