川北医学院学报2018，Vol.33Issue(1)：134-137,4.DOI:10.3969/j.issn.1005-3697.2018.01.040
CD4+CD25+调节性T细胞在肿瘤免疫中的研究进展
The progress in CD4+CD25+regulatory T cell and anti-tumor immune research
摘要
Abstract
Regulatory T cell(Tregs) is a kind of T cell subsets with immunosuppressive function,which plays a key role in im-munotolerance.And it is correlated with autoimmune diseases,transplantation tolerance,and tumor immunologic suppression.Recently, an increasing number of studies focus on the role of Tregs in cancer treatment.It was found that Tregs play a key role in progression and development of human malignant tumors.Tregs can affect the effector T cells and anti-tumor immunity by cell-cell contact,cytokines, and cell metabolism interference.Therefore,the immunotherapy which aims at Tregs can be very useful in treating malignant tumors in future.In this paper,the characteristics of Tregs and its relationship with tumor immunotherapy are reviewed.关键词
CD4+CD25+调节性T细胞/肿瘤免疫/肿瘤治疗Key words
CD4 +CD25 +regulatory T cell/Tumor immunity/Cancer therapy分类
医药卫生引用本文复制引用
胡子龙,何长征,邢晓伟,胡时栋,李宇轩,宋林杰,王玉锋,杜晓辉..CD4+CD25+调节性T细胞在肿瘤免疫中的研究进展[J].川北医学院学报,2018,33(1):134-137,4.基金项目
国家自然科学基金(61170123) （61170123）
