重庆医学2017，Vol.46Issue(35)：4971-4973,3.DOI:10.3969/j.issn.1671-8348.2017.35.023
血清sFas和sLOX-1与急性冠状动脉综合征发生及发展的相关性研究
Study on correlation between serum sFas and sLOX-1 with occurrence and development of acute coronary syndrome
胡艳清 1马建群 2孙子雯 2冯真真 3徐会圃4
作者信息
- 1. 济南大学山东省医学科学院医学与生命科学学院,济南250029
- 2. 山东省医学科学院附属医院心内科,济南250031
- 3. 山东省医学科学院附属医院医务部,济南250031
- 4. 滨州医学院附属医院心内科,山东滨州256600
- 折叠
摘要
Abstract
Objective To investigate the correlation between serum sFas and sLOX-1 with occurrence and development of acute coronary syndrome (ACS).Methods A total of 52 patients definitely diagnosed ACS (ACS group) by coronary artery angiography (CAG) were enrolled,including 23 cases of unstable angina (UA group) and 29 cases of acute myocardial infarction (AMI group),and contemporaneous 58 cases of non-coronary arterial stenosis confirmed by CAG were selected as the control group (NC group).The serum levels of sFas and sLOX-1 were measured by enzyme linked immunosorbent assay.Results Compared with the NC group,the serum levels of sFas and sLOX-1 in the ACS group were increased,the serum levels of sFas and sLOX-1 in the AMI group and UA group were higher than those in the NC group,moreover which in the AMI group were higher than those in the UA group (P＜0.01).The serum sFas level in the ACS group was positively correlated with the sLOX-1 level (r=0.825,P=0.001),but both had no obvious correlation with the serum levels of CK-MB and cTnⅠ (P＞0.05).Conclusion High levels of serum sFas and sLOX-1 may be the risk factors of ACS.关键词
急性冠状动脉综合征/可溶性Fas/可溶性凝集素样氧化低密度脂蛋白受体-1/细胞凋亡/炎性反应Key words
acute coronary syndrome/soluble Fas/soluble lectin-like oxidized low-density lipoprotein receptor-1/apoptosis/inflammatory response分类
医药卫生引用本文复制引用
胡艳清,马建群,孙子雯,冯真真,徐会圃..血清sFas和sLOX-1与急性冠状动脉综合征发生及发展的相关性研究[J].重庆医学,2017,46(35):4971-4973,3.
