重庆医学2018，Vol.47Issue(9)：1153-1154,1157,3.DOI:10.3969/j.issn.1671-8348.2018.09.001
磁共振扩散张量成像在大鼠C6脑胶质瘤分级中的应用研究
Application of magnetic resonance diffusion tensor imaging in rat C 6 glioma grading
摘要
Abstract
Objective To explore the application value of fractional anisotropy(FA)values of magnetic resonance diffusion tensor imaging(DTI)parameters in rat rat glioma grading.Methods Sixty-seven female Wistar rats were divided into the experi-mental group(n=57)and control group(n=10)according to the random number table method.All the surviving rats were exam-ined by 3.0T DTI at 1-2 weeks(22 cases)and 3-4 weeks(35 cases)after inoculation,and the FA values of the tumor were ob-tained and compared with the pathological results.Results Among 57 tumor-loading rats,there were 18 low-grade gliomas and 39 high-grade gliomas.DTI showed that the FA value of high-grade gliomas was higher than that of the low-grade glioma,the differ-ence was statistically significant[(0.167 ± 0.035)vs.(0.147 ± 0.015),t=2.34,P<0.05].Conclusion The FA value of DTI pa-rameters can provide accurate,reliable and noninvasive imaging information for preoperative glioma grading.关键词
胶质瘤/磁共振弥散张量成像/部分各向异性分数/大鼠,WistarKey words
rat/glioma/diffusion tensor imaging/fractional anisotropy/rat/Wistar分类
医药卫生引用本文复制引用
李香营,蒋锡丽,杨光,陈建强,战跃福,唐少虎,韩向君..磁共振扩散张量成像在大鼠C6脑胶质瘤分级中的应用研究[J].重庆医学,2018,47(9):1153-1154,1157,3.基金项目
国家自然科学基金资助项目(81360228) （81360228）
海南省自然科学基金资助项目(813259) （813259）
海口市重点科技计划项目(2013-72、2011-0145) （2013-72、2011-0145）
海南省卫生厅项目(琼卫2011-67). （琼卫2011-67）
