重庆医学2018，Vol.47Issue(9)：1155-1157,3.DOI:10.3969/j.issn.1671-8348.2018.09.002
火针治疗稳定期白癜风的临床疗效及其CLSM图像特点
Clinical effect of fire needle in treating vitiligo and its CLSM image characteristics
摘要
Abstract
Objective To evaluate the clinical effect of fire needle in treating vitiligo and the characteristics of vitiligo image by the confocal laser scanning microscope(CLSM).Methods The randomized self-controlled experiment design was adopted.Each patient selected two symmetric or adjacent white patches and randomly received the fire needle treatment or tacrolimus treatment. The duration of treatment was 3 months.The CLSM images of white patches were recorded before treatment and after 3,6 times of fire needle treatment.Results Among 41 cases of stable stage vitiligo,The effective rates of the fire needle group and tacrolimus group were 82.9% and 78.0% respectively,and the difference was not statistically significant(P>0.05).After fire needle treat-ment,dentritic melanin cells appeared,the pigment granules gradually appeared around the basal layer and corpora papillare,and formed the pigment ring.Conclusion Fire needle and tacrolimus have the similar effect in treating vitiligo,moreover CLSM can be used as the non-invasive,objective and reliable detection means of the recovery of vitiligo melanocyte.关键词
火针/白癜风/皮肤共聚焦激光扫描显微镜Key words
fire needle/vitiligo/confocal laser scanning microscopy分类
医药卫生引用本文复制引用
王禹毅,刁庆春,宁春竹,温馨,余音,徐伟,陶春蓉..火针治疗稳定期白癜风的临床疗效及其CLSM图像特点[J].重庆医学,2018,47(9):1155-1157,3.基金项目
国家自然科学基金资助项目(81503588) （81503588）
国家中医药重点学科专项经费资助(2209020301) （2209020301）
重庆市卫生和计生委中医药科技项目(ZY20150237) （ZY20150237）
重庆市基础与前沿研究计划项目(cstc2016jcyjAX0002) （cstc2016jcyjAX0002）
重庆市社会民生科技创新专项(cstc2016shms-zd10001-4) （cstc2016shms-zd10001-4）
重庆市基础与前沿研究计划项目(cstc2015jcyjA10113). （cstc2015jcyjA10113）
