南方医科大学学报2018，Vol.38Issue(3)：239-242,4.DOI:10.3969/j.issn.1673-4254.2018.03.01
抗生素过敏反应所致Purtscher样视网膜病变:1例报告及文献复习
Purtscher-like retinopathy associated with antibiotic anaphylaxis
摘要
Abstract
We report a case of an 18-year-old woman with systemic antibiotic anaphylaxis who presented anasarca and bilateral visual loss two weeks after the intravenous use of pazufloxacin.Ancillary fundus tests revealed bilateral cotton-wool spots, Purtscher flecken, edema, and retinal arteriolar occlusion around the optic disc.After pulse corticosteroid, administration of anti-anaphylactic agent, and general support therapy for one month, the patient showed a favorable change, with the symptoms lessened or free systemically,except the continuous aggravation of fundus ischemic change. After two intravitreal injections of Ranibizumab, there were still a large area of capillary non-perfusion and neovacularizations in the binocular retina, resulting in vitreous hemorrhage. The patient's visual acuity had still light perception after right-eye vitrectomy and presented no improvement during the postoperative follow-up of two years.Literature review revealed that there were many causes associated with Purtscher-like retinopathy, and the consequent visual impairment varied significantly. Prompt management of the underlying condition is crucial in giving the patient the best chance to restore vision.关键词
Purtscher-like视网膜病变/Perstscher视网膜病变/过敏反应/抗生素Key words
Purtscher's retinopathy/Purtscher-like retinopathy/antibiotic/anaphylaxis引用本文复制引用
黄志翾,曾志冰,徐筑萍..抗生素过敏反应所致Purtscher样视网膜病变:1例报告及文献复习[J].南方医科大学学报,2018,38(3):239-242,4.基金项目
国家重大科学仪器设备开发专项(2012YQ12008005) Supported by National Major Scientific Equipment Program of China(2012YQ12008005). （2012YQ12008005）
