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改良环状软骨上喉部分切除术治疗中晚期喉癌的疗效及生存质量评估

王茹 陈学军 廉猛 房居高 马泓智 冯凌 钟琦 侯丽珍 李平栋 黄志刚 陈晓红

中国耳鼻咽喉头颈外科2017,Vol.24Issue(11):557-560,4.
中国耳鼻咽喉头颈外科2017,Vol.24Issue(11):557-560,4.DOI:10.16066/j.1672-7002.2017.11.002

改良环状软骨上喉部分切除术治疗中晚期喉癌的疗效及生存质量评估

Survival and life quality evaluation on advanced laryngeal cancer treated with modified supracricoid partial laryngectomy

王茹 1陈学军 1廉猛 1房居高 1马泓智 1冯凌 1钟琦 1侯丽珍 1李平栋 1黄志刚 1陈晓红1

作者信息

  • 1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),头颈部分子病理诊断北京市重点实验室,北京 100730
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摘要

Abstract

OBJECTIVE To evaluate the survival and functional outcomes of advanced laryngeal squamous cell carcinoma after modified supracricoid partial laryngectomy(SCPL).METHODS We selected 65 laryngeal cancer patients treated with modified supracricoid partial laryngectomy from 2002 to 2015 in our hospital.Among them,62 cases were males,3 cases were females with an age ranged from 35 to 80 years(median age 58 years)There were 26 cases with T2 stage,32 cases with T3 stage and 7 cases with T4 stage.We selected 120 laryngeal cancer patients treated with vertical partial laryngectomy at the same period as control.Then we evaluated the functional outcomes of modified supracricoid partial laryngectomy group compared with vertical partial hemilaryngectomy group.RESULTS The 5-year cumulative survival rate and decannulation rate were 82.3% and 98.3% for supracricoid laryngectomy group respectively.Decannulation ratewas 86.1% for vertical partial hemilaryngectomy group(P<0.05).However,there was no significant difference between supracricoid partial laryngectomy group and vertical partial laryngectomy group in pronunciation evaluation and abnormal deglutition.CONCLUSION Modified supracricoid partial laryngectomy is a good choice for local advanced laryngeal squamous cell carcinoma.

关键词

喉肿瘤/预后/生活质量/环状软骨上喉部分切除术

Key words

Laryngeal Neoplasms/Prognosis/Quality of Life/supracricoid partial laryngectomy

引用本文复制引用

王茹,陈学军,廉猛,房居高,马泓智,冯凌,钟琦,侯丽珍,李平栋,黄志刚,陈晓红..改良环状软骨上喉部分切除术治疗中晚期喉癌的疗效及生存质量评估[J].中国耳鼻咽喉头颈外科,2017,24(11):557-560,4.

基金项目

北京市医管局临床技术创新项目(XMLX201311)和国家自然科学基金面上项目(81473499)联合资助 (XMLX201311)

中国耳鼻咽喉头颈外科

OACSCDCSTPCD

1672-7002

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