中国耳鼻咽喉头颈外科2017，Vol.24Issue(11)：593-596,4.DOI:10.16066/j.1672-7002.2017.11.010
112例鼻腔NK/T细胞淋巴瘤的预后分析
Prognostic factors analysis of nasal NK/T cell lymphoma
陈琦 1王悠 1巴云鹏 1张远1
作者信息
- 1. 郑州大学第一附属医院鼻科,河南郑州450000
- 折叠
摘要
Abstract
OBJECTIVE To investigate the prognosis of nasal NK/T cell lymphoma.METHODS The clinical data of 112 patients with a primary diagnosis of nasal NK/T cell lymphoma treated at the First Hospital of Zhengzhou University between January 2010 and June 2017 were studied.The association between clinical parameters and survival rate was evaluated by Kaplan-Meier method and Cox regression model.RESULTS The 1-,3-,5-year overall survival were 92％,72％ and 54％ respectively.Single factor analysis displayed that age,gender,the level of albumin,the expression level of Ki-67,treatment model,complete response rate to the primary treatment and the interval between symptom onset to diagnosis were related to the prognosis factors.Multivariate analysis showed that the interval of first time of symptom onset to the time of diagnosis and the positive rate of Ki-67 more than 50％ were the independent risk factors for the prognosis of nasal NK/T lymphoma.CONCLUSION The interval of symptom onset to the time of diagnosis and the positive rate of Ki-67 may be independent prognostic factors for NK/T cell lymphoma.关键词
淋巴瘤,结外NK-T细胞/鼻腔/预后/Ki-67抗原Key words
Lymphoma, Extranodal NK-T-Cell/Nasal Cavity/Prognosis/Ki-67 Antigen引用本文复制引用
陈琦,王悠,巴云鹏,张远..112例鼻腔NK/T细胞淋巴瘤的预后分析[J].中国耳鼻咽喉头颈外科,2017,24(11):593-596,4.
