国际生殖健康/计划生育杂志2018，Vol.37Issue(1)：20-23,4.
血清PRO-BNP水平与子痫前期围生期结局关系的回顾性研究
A Retrospective Study on Serum PRO-BNP for Evaluating the Perinatal Outcome of Pre-Eclampsia
摘要
Abstract
Objective:To explore the application of serum pro-B-type natriuretic peptide (PRO-BNP) in pre-eclampsia patients as a potential predictor of maternal and fetal outcomes.Methods:A total of 111 preeclampsia women were enrolled in this retrospective study.The level of serum PRO-BNP was measured by immunofluorescence.According to the levels of PRO-BNP,patients were divided into two groups:the normal group (n=85) and the increased group (n=26).The differences of pregnant outcomes were compared between the two groups.Results:The increased group had the lower rate of the expectant treatment (7.7％ vs.36.5％,x2=7.893,P=0.005) and the higher incidences of proteinuria and pleural effusion when compared with the normal group (both P＜0.05).However,there were no significant differences in the fetal distress,the rate of premature infant,the newborn treatment transferred to pediatric department,the body mass of newborn and the Apgar score between the two groups (all P＞0.05).Conclusions:The level of serum PRO-BNP was related to the severity of organ injury in those pre-eclampsia women.However,PRO-BNP could not be a predictor of the newborn prognosis.关键词
子痫前期/回顾性研究/预后/B型脑利钠肽Key words
Pre-eclampsia/Retrospective studies/Prognosis/Pro B-type natriuretic peptide引用本文复制引用
倪晴,张世昌,陈文玮,张国英,陈黎..血清PRO-BNP水平与子痫前期围生期结局关系的回顾性研究[J].国际生殖健康/计划生育杂志,2018,37(1):20-23,4.基金项目
国家自然科学基金(81300507) （81300507）
