国际生殖健康/计划生育杂志2018,Vol.37Issue(1):57-61,75,6.
多囊卵巢综合征病因、发病机制及治疗的最新研究进展
Research Progress in the Etiology, Pathogenesis and Treatment of Polycystic Ovary Syndrome
摘要
Abstract
Polycystic ovary syndrome (PCOS) is one of the common endocrine disorders in women of reproductive age.In addition to their inherent polycystic ovary,hyperandrogenism and ovarian dysfunction,there are obesity,type 2 diabetes,dyslipidemia and other metabolic abnormalities.With the change of living environment,the incidence of PCOS gradually increases.If the condition is not improved for a long time,it will not only affect reproductive health,but also affect general health.Although we have made a little progress in understanding PCOS,the complicated etiology and heterogeneous clinical manifestations suggested that the comprehensive treatment was very important for those PCOS women.For those PCOS women with fertility demand,the ovulation induced with drugs will help them to get pregnancy.However,the objective of the ovulation induction should be to get a single developed follicle,and to avoid the multiple developing follicles.In IVF/ICSI cycles,an excess of developing follicles should be avoided so as to prevent ovarian hyperstimulation syndrome (OHSS) and multiple pregnancy.The research progress of the etiology,pathogenesis and treatment of PCOS were briefly discussed in this review.关键词
多囊卵巢综合征/雄激素类/胰岛素抗药性/高胰岛素血症/二甲双胍Key words
Polycystic ovary syndrome/Androgens/Insulin resistance/Hyperinsulinism/Metformin引用本文复制引用
冷芹..多囊卵巢综合征病因、发病机制及治疗的最新研究进展[J].国际生殖健康/计划生育杂志,2018,37(1):57-61,75,6.基金项目
安徽省自然科学基金项目(1708085MH214) (1708085MH214)