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肺腺样囊性癌的分子特征

何诚 陈刚 黄榕芳 刘伟 庄武 方美玉 吴标 郑晓彬 许春伟 陈燕坪

临床与病理杂志2017,Vol.37Issue(11):2352-2356,5.
临床与病理杂志2017,Vol.37Issue(11):2352-2356,5.DOI:10.3978/j.issn.2095-6959.2017.11.011

肺腺样囊性癌的分子特征

Molecular features of pulmonary adenoid cystic carcinoma

何诚 1陈刚 1黄榕芳 1刘伟 1庄武 2方美玉 3吴标 2郑晓彬 2许春伟 1陈燕坪1

作者信息

  • 1. 福建医科大学附属福建省肿瘤医院病理科,福州350014
  • 2. 福建医科大学附属福建省肿瘤医院胸部肿瘤内科,福州350014
  • 3. 浙江省肿瘤医院综合内科,杭州310022
  • 折叠

摘要

Abstract

Objective:To investigate the molecular characteristics of pulmonary adenoid cystic carcinoma (PACC).Methods:From July 2013 to December 2016,15 PACC patients received treatment.All the patients were diagnosed by pathology.We retrospectively reviewed the clinical data and genetic state.Results:EGFR mutation rate was 6.67% (1/15),and it was 19del,the relationship between EGFR gene status and gender (P=1.000),age (P=1.000),smoking status (P=1.000) and stage (P=1.000) were no significant,and ALK fusion and ROS1 fusion gene was not detected.Conclusion:Gene change exists PACC,and the gene detection cannot be ignored in PACC.

关键词

腺样囊性癌/分子特征/基因检测

Key words

adenoid cystic carcinoma/molecular features/gene detection

引用本文复制引用

何诚,陈刚,黄榕芳,刘伟,庄武,方美玉,吴标,郑晓彬,许春伟,陈燕坪..肺腺样囊性癌的分子特征[J].临床与病理杂志,2017,37(11):2352-2356,5.

基金项目

国家临床重点专科建设项目(2013) (2013)

福建省卫生计生青年科研课题(2017-2-7) (2017-2-7)

福建省医学创新课题(2017-CXB-1).This work was supported by National Clinical Key Specialty Construction Program (2013),Fujian Provincial Youth Health Science Research Project(2017-2-7) and Fujian Medical Innovation Project (2017-CXB-1),China. (2017-CXB-1)

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