临床与病理杂志2017，Vol.37Issue(12)：2549-2554,6.DOI:10.3978/j.issn.2095-6959.2017.12.006
中药联合护肝功法治疗慢性乙型肝炎后肝纤维化的效果
Chinese herbal medicine combined with liver protection therapy in patients with liver fibrosis after chronic hepatitis B
摘要
Abstract
Objective:To investigate the effect of Chinese herbal medicine combined with liver protection therapy on liver fibrosis in patients with chronic hepatitis B.Methods:A total of 113 patients enrolled in the requirements were randomly divided into observation group (57 cases) and control group (56 cases),two groups were treated with routine application of Western medicine combined with traditional Chinese medicine treatment,the observation group based on the application of liver intervention method,treatment time was 3 months.The liver function,liver fibrosis index and quality of life were compared between the two groups before and after treatment.Results:In liver function,TBIL,ALT and AST of the two groups were significantly improved,and the observation group were significantly lower than the control group after intervention (P＜0.05);serum hyaluronic acid (HA),laminin (LN),type Ⅳ collagen (Ⅳ-C) and type Ⅲ procollagen (PCⅢ)were significantly improved in the two groups after intervention (P＜0.05),and the observation group were significantly lower than the control group after intervention (P＜0.05).In the quality of life,each dimension scores of Short Form 36 Health survey Questionnaire (SF-36) of the observation group was higher than that of the control group (P＜0.05),and the observation group was higher than that of the control group after intervention (P＜0.05).Conclusion:Chinese herbal medicine combined with liver strengthening exercise can effectively improve the liver function of patients with liver fibrosis after chronic hepatitis B,and improve the quality of life.关键词
慢性乙型肝炎/肝纤维化/中药/护肝功法Key words
chronic hepatitis B/hepatic fibrosis/traditional Chinese medicine/liver protection therapy引用本文复制引用
梁惠珠,张文茹..中药联合护肝功法治疗慢性乙型肝炎后肝纤维化的效果[J].临床与病理杂志,2017,37(12):2549-2554,6.基金项目
2012年建设中医药强省立项资助科研课题[粤中医(2012)23号].This work was supported by the Construction of Strong Province of Traditional Chinese Medicine in 2012 to Support Scientific Research Projects,China [Guangdong traditional Chinese medicine (2012)No.23]. （2012）
