临床与病理杂志2017，Vol.37Issue(12)：2639-2642,4.DOI:10.3978/j.issn.2095-6959.2017.12.021
膀胱癌组织中HSPC238的表达及其临床意义
HSPC238 mRNA expression in bladder cancer and its clinical significance
摘要
Abstract
Objective:To detect HSPC238 mRNA expression in bladder cancer and explore its clinical significance.Methods:A total of 116 patients of bladder cancer were enrolled in this study.The non-cancerous tissues beside the tumor were taken as controls.Real-time PCR analysis was used to detect HSPC238 mRNA expression.Results:HSPC238 in bladder cancer tissue was 0.172±0.023,which was lower than that of 0.304±0.051 in control tissue (P＜0.01).HSPC238 in Ⅲ and ⅣV stage group was 0.137±0.017,which was lower than that of 0.194±0.028 in Ⅰ and Ⅱ stage group (P＜0.01).HSPC238 of patients with muscular layer infiltration was 0.161±0.021,which was lower than that of 0.195±0.029 in non-muscular layer infiltration patients (P＜0.05).HSPC238 in median and low differentiation group was 0.156±0.021,which was lower than that of 0.205±0.037 in well differentiation group (P＜0.05).HSPC238 in lymph node metastasis group was 0.147±0.016,which was lower than that of 0.181±0.022 in non-lymph node metastasis group (P＜0.05).Conclusion:Low expression of HSPC238 was detected in bladder cancer,which was related to clinical stages,lymph node metastasis,and tumor differentiation of bladder cancer.关键词
膀胱癌/HSPC238基因/荧光定量-PCRKey words
bladder cancer/HSPC238 gene/real-time PCR analysis引用本文复制引用
卢志承,符志龙,陈世梁,吴文川..膀胱癌组织中HSPC238的表达及其临床意义[J].临床与病理杂志,2017,37(12):2639-2642,4.
