河北医学2017，Vol.23Issue(12)：1937-1940,4.DOI:10.3969/j.issn.1006-6233.2017.12.001
1032例男性不育症患者细胞遗传学分析
Cytogenetic Analysis of 1032 Male Infertility Patients
摘要
Abstract
Objective:To investigate the detection rate and abnormal type of abnormal chromosome karyotype in infertile patients.Methods:1032 infertile patients' peripheral blood lymphocytes were detected by G banding karyotype analysis.Results:51 cases of chromosomal abnormalities were found in 1032 male patients,the detection rate was 4.94％.Among them,there are 3 cases of sex chromosomal abnormalities,11 cases of autosmal abnormalities,37 cases of chromosome polymorphism changed,the 37 cases state including 8 cases of sex chromosomal polymorphism changed and 29 cases of autosomal polymorphic changed.Most clinical manifestations are weak symptoms,azoospermia and spouse repeated abortion.Conclusion:In male infertility patients,not only need to carry out routine analysis of semen,but also carry their abnormal chromosomes or chromosome polymorphisms detected to prevent patients from transmitting these abnormal chromosomes to the next generation,resulting in its offspring of infertility.关键词
染色体多态性/染色体异常/不育症Key words
Chromosome polymorphism/Chromosomal abnormality/Infertility引用本文复制引用
柴蓓蓓,何培,王惠莹,刘浏,张若鹏,袁彩..1032例男性不育症患者细胞遗传学分析[J].河北医学,2017,23(12):1937-1940,4.基金项目
大理大学博士科研启动费项目,(编号:KYBS201612) （编号:KYBS201612）
大理大学第一附属医院第二批重点学(专)科建设项目,(编号:2017ZD02) （专）
