河北医学2017,Vol.23Issue(12):2005-2009,5.DOI:10.3969/j.issn.1006-6233.2017.12.020
Amplatzer封堵器在左心耳封堵术治疗出血风险性心房颤动患者中的临床疗效
Clinical Effect on Left Atrial Appendage Occlusion with the Amplatzer Cardiac Plug in Atrial Fibrillation Patients with Increased Bleeding Risk
关欣 1白志生1
作者信息
- 1. 陕西省宝鸡市人民医院心血管内科,陕西 宝鸡 721000
- 折叠
摘要
Abstract
Objective:To investigate the clinical effect on left atrial appendage occlusion with the amplatzer cardiac plug in atrial fibrillation patients with increased bleeding risk.Methods:60 atrial fibrillation patients with increased bleeding risk by Left atrial appendage occlusion admitted in cardiology department of our hospital during March 2013 to May 2015 were selected as LAAO group and 80 atrial fibrillation patients with increased bleeding risk for the same period as the control group.The plasma ANP,left ventricular ejection fraction (LVEF) and LAA peak,1 year and 2 year survival rates were compared of two groups before and after treatment.Results:The plasma ANP level of LAAO Group after 72 h and 3 months postoperative were significantly decreased.Mter 3 months,the ANP level back to 26.56±5.17 (pg/ml),there was no statistically significant difference compared with control group (P>0.05).and recovered to preoperative levels after 3 months postoperative.Compared with control group,the difference was statistically significant (P<0.05).The cardiac function index of two groups were significantly better than before treatment and the improvement of observation group was significantly better than control group,the difference was statistically significant (P<0.05).The 1 year survival rates (88.3% vs72.5 %)and 2 year survival rates(53.3% vs38.8 %) of two groups were significant difference (P< 0.05).Conclusion:LAAO with ACP seems to improve the combination of survival,improve heart function and has good application prospect in patients with atrial fibrillation and increased bleeding risk.关键词
Amplatzer封堵器/左心耳封堵术/出血/心房颤动Key words
Amplatzer cardiac plug/Left atrial appendage occlusion/Bleeding/Atrial fibrillation引用本文复制引用
关欣,白志生..Amplatzer封堵器在左心耳封堵术治疗出血风险性心房颤动患者中的临床疗效[J].河北医学,2017,23(12):2005-2009,5.