河北医学2017，Vol.23Issue(12)：2061-2065,5.DOI:10.3969/j.issn.1006-6233.2017.12.039
初诊原发性高血压患者血压变异性与尿微量白蛋白的相关性研究
Relationship between Blood Pressure Variability and Microalbuminuria in patients with Primary Hypertension
摘要
Abstract
Objective:To investigate the relationship of BPV evaluation index:the actual average variation (ARV) and standard deviation (SD) of the pros and cons through the analysis of newly diagnosed patients with essential hypertension blood pressure variability (BPV) and urinary albumin (MA).Method:A total of 223 of primary hypertension patients were selected,averaged (50.9± 12.1) years old.all the patients were not taking autihypertensive drugs,according to microalbuminuria divided into positive-MA group (71 case) and negative-MA group (152 case).Baseline data,24h mean systolic and diastolic pressure,nocturnal systolic and diastolic blood pressure,daytime systolic and diastolic blood pressure,and SD and ARV of the corresponding period were compared,to analyze the relationship between MA and mean blood pressure,SD,ARV,and so on.Result:The SD (24h SBP,dSBP,nSBP),ARV (24hSBP,dSBP) in positive-MA group were higher than the negative-MA group,and there was statistical significance (P＜0.05);but SD,ARV of diastolic blood pressure,ARV of nighttime systolic blood pressure are no significant difference between the two groups (P＞0.05).②Logistic regression analysis showed that 24h mean systolic blood pressure,SD of diurnal systolic pressure,SD of nocturnal systolic blood pressure,ARV of 24h systolic blood pressure were independent risk factors of MA.Conclusion:Blood pressure variability is an independent risk factor for predicting early renal function impairment,and SD and ARV can be used to assess blood pressure variability.关键词
高血压/血压变异性/尿微量白蛋白/平均实际变异Key words
Essential hypertension/Blood pressure variability/Microalbuminuria/Average real variability引用本文复制引用
杨静,张小玲,苏浩,严激,张灿,游杨扬..初诊原发性高血压患者血压变异性与尿微量白蛋白的相关性研究[J].河北医学,2017,23(12):2061-2065,5.基金项目
安徽省软科学研究项目,(编号:12020503078) （编号:12020503078）
