河北医学2018，Vol.24Issue(3)：382-385,4.DOI:10.3969/j.issn.1006-6233.2018.03.008
丹参川芎嗪注射液对重度烧伤患者炎性因子影响及预防脓毒症发生效果分析
Effect of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection on the Inflammatory Factors of Severe Burn Patients and the Prevention of Sepsis
摘要
Abstract
Objective:To investigate the effect of ligustrazine injection on inflammatory cytokines in se-vere burn patients and the prevention of sepsis.Methods:80 patients with severe burn admitted to our hospital from April 2013 to March 2017 were randomly divided into two groups.Patients in the control group were given routine treatment. Patients in the observation group were treated with ligustrazine injection. The two groups of patients with inflammatory factors, other diseases related parameters and sepsis prevention effect were com-pared. Results:The levels of TNF-α,IL-1,IL-6,CRP and PCT in the observation group were significantly lower than those in the control group on the 1st,3rd,7th,10th and 14th day after treatment. ALT and AST levels were significantly lower than the control group,there was a significant difference(P <0.05);SIRS inci-dence was significantly lower than the control group, there was a significant difference (P <0.05). Conclu-sion: The effect of Salviae Miltiorrhizae injection on inflammatory factors and prevention of sepsis in patients with severe burn has significant reference value.关键词
丹参川芎嗪注射液/重度烧伤/脓毒症Key words
Salvia ligustrazine injection/Severe burn/Sepsis引用本文复制引用
林颜,阮树斌,陈晓东,张凤刚,杨荣华,林泽鹏..丹参川芎嗪注射液对重度烧伤患者炎性因子影响及预防脓毒症发生效果分析[J].河北医学,2018,24(3):382-385,4.基金项目
广东省科技计划项目,(编号:2013B03052) （编号:2013B03052）
