摘要
Abstract
Objective: To investigate the abnormal uterine bleeding in perimenopausal patients, using the clinical effect of marvelon. Methods:84 cases of abnormal uterine bleeding in the perimenopausal period were selected and divided into two groups randomly, 42 cases in each group. Mifepristone (1 times /d, 12. 5mg each time) was used as the control group, and Desogestrel and Ethinylestradiol Tablets (2-3 /d, 3-4 tablets each time,1 /d) was used as the observation group. The levels of sex hormones (follicle stimulating hormone (FSH),progesterone(P),estradiol(E2),luteinizing hormone(LH)),uterine volume and endo-metrial thickness,adverse reactions and therapeutic effects in two groups after 3 courses of treatment were ob-served. Results: The levels of FSH, P, E2 and LH in the observation group were significantly lower than those in the control group (P<0.05). The measurements of uterine volume and endometrium thickness in the observation group were less than those of the control group(P<0.05). The total effective rate of clinical treat-ment in the control group was 80.95%,and the total effective rate in the observation group was 92.86% (P<0.05). The adverse incidence rate of the control group was 7.14%,and the adverse incidence rate of the ob-servation group was 19.05%(P<0.05).Conclusion:Compared with mifepristone in the treatment of abnormal uterine bleeding in perimenopausal period, Desogestrel and Ethinylestradiol Tablets has a more significant clinical effect,and improves the indicators and uterus of patients more obviously,but it is easy to cause acne and obesity,so we should pay attention to drug reactions.关键词
围绝经期/异常子宫出血/去氧孕烯炔雌醇片Key words
Perimenopausal/Abnormal uterine bleeding/Desogestrel and etlingylestradiol tablets
