河北医学2018，Vol.24Issue(3)：517-520,4.DOI:10.3969/j.issn.1006-6233.2018.03.046
血管性痴呆患者血清炎症因子和生化指标的检测及临床意义
Detection and Clinical Significance of Serum Inflammatory Factors and Biochemical Indexes in patients with Vascular Dementia
张作念 1顾伟 2王志晔 1章慧 1倪梦园 1潘锡近3
作者信息
- 1. 江苏省南京市梅山医院神经内科, 江苏 南京 210039
- 2. 江苏省南京市浦口区中医院神经内科, 江苏 南京 211800
- 3. 江苏省南京市鼓楼医院神经内科, 江苏 南京 210009
- 折叠
摘要
Abstract
Objective:To explore the clinical significance of detecting serum inflammatory factors and bi-ochemical indexes in patients with vascular dementia(VD) so as to provide reference for the clinical diagnosis of patients with this disease.Methods:82 patients with vascular dementia(observation group) admitted to our hospital from October 2012 to October 2016 and 85 normal persons(control group) who underwent health ex-amination in our hospital during the same period were enrolled in this study.Serum levels of inflammatory cyto-kines and life indicators,analysis of the two groups were included in the indicators of the differences between the levels. Results:The levels of IL-1β,TNF-α and IL-6 in the observation group were[(62.69 ± 31.08) pg / mL],[(8.41 ± 2.06) foml / mL] and[(10.97 ± 5.12) pg / mL] were significantly higher in the con-trol group than those in the control group (P <0.05) The levels of Hcy, HDL-C, LDL-C, triglyceride and apolipoprotein A were [(37.51 ± 19.34) umoL / L,0.90 ± 0.23 nmoL / L,3.14 ± 1.11 nmoL / L,1.74 ± 1.02 mmoL / L, / L],there was significant difference between each index level and the control group (P <0.05). There was no significant difference in the levels of other inflammatory factors and biochemical indexes between the two groups (P> 0.05). Conclusion:There are differences in inflammatory factors and biochemi-cal indicators between vascular dementia patients and normal persons. Joint detection of inflammatory factors and biochemical indicators is helpful for clinical diagnosis of vascular dementia patients.关键词
血管性痴呆/炎症因子/生化指标Key words
Vascular dementia/Inflammatory factors/Biochemical indexes引用本文复制引用
张作念,顾伟,王志晔,章慧,倪梦园,潘锡近..血管性痴呆患者血清炎症因子和生化指标的检测及临床意义[J].河北医学,2018,24(3):517-520,4.
