中国实用神经疾病杂志2017，Vol.20Issue(22)：40-43,4.DOI:10.3969/j.issn.1673-5110.2017.22.011
血清25-羟基维生素D水平与急性缺血性脑卒中严重程度的分析
Study on the correlation between serum 25-hydroxyvitamin D levels and severity of acute ischemic stroke
摘要
Abstract
Objective To discuss the correlation between serum25-hydroxyvitamin D (25 (OH) D) levels and the severity of the patients with acute ischemic stroke.Methods 169 patients with acute ischemic stroke were continuously assessed from the Department of Neurology,the Affiliated Sheng Jing Hospital of China Medical University.Demographic data and history of risk factors were obtained at admission.The determination of serum 25 (OH) D levels were measured and the NIHSS was improved at admission.Results Light Stroke Group (NIHSS score＜5 min) has 116 cases,heavy stroke group (NIHSS score≥5points) has 53 cases,two groups had significant differences in serum 25 (OH) d level,cerebrovascular history,fasting glucose and diastolic blood pressure (P＜0.05),the multifactor analysis revealed that serum 25 (OH) d level was an independent predictor in ischemic stroke (by assessing NIHSS) and 25 (OH) d was a protective factor in ischemic stroke (or value =0.908,95％) CI:0.859-0.96,P＜0.01,fasting blood glucose and diastolic pressure were independent predictors of ischemic stroke and the risk factors for ischemic stroke,fasting blood glucose (or value=1.213,95 ％ CI:1.019～ 1.444,P＜0.05),diastolic pressure (or value=1.037,95 ％ CI:1.005～1.069,P＜0.05).Conclusion Serum 25 (OH) d,fasting blood glucose,diastolic pressure are independent predictors of severity of acute ischemic stroke,and 25 (OH) d is a protective factor,fasting blood glucose and diastolic pressure are the risk factors.关键词
缺血性脑卒中/25-羟基维生素D/严重程度/空腹血糖/舒张压Key words
Ischemic stroke/25-hydroxyvitamin D/Severity/Fasting glucose/Diastolic blood pressure分类
医药卫生引用本文复制引用
方厚盈,邓小容,杜敏,万鸿平,郭阳..血清25-羟基维生素D水平与急性缺血性脑卒中严重程度的分析[J].中国实用神经疾病杂志,2017,20(22):40-43,4.基金项目
辽宁省科技计划项目(2012225021) （2012225021）
