解放军医学杂志2018，Vol.43Issue(1)：69-74,6.DOI:10.11855/j.issn.0577-7402.2018.01.14
钴锰放射性核素皮肤沾染去污剂的初步研制
Preparation of decontaminant for skin radioactive isotopes contamination of Co2+ and Mn2+
原维鸿 1沈先荣 2刘琼 2何颖 2陈伟 2王庆蓉 2罗群 2侯登勇 2唐雪2
作者信息
- 1. 201306上海 上海海洋大学食品学院
- 2. 200433上海 第二军医大学海军医学研究所防护医学研究室
- 折叠
摘要
Abstract
Objective To develop a detergent for decontamination of Co2+ and Mn2+ on skin.Methods Single-factor experimental and orthogonal experimental designs were performed to study the formula composition of the decontaminant.The skin irritation experiment was performed and assessed according to the standard method.The detergent was prepared according the conventional process of showering gel.The pH,ethylenediaminetetraacetic acid (EDTA) level,total active substances of the detergent,and its stability were evaluated according to the chemical method recommended in the national standard GB/T 13173-2008.The decontamination efficiency on stable isotopes of Co2+ and Mn2+ contamination was measured on the back of hand skin of volunteers.Results The formula composition of the decontaminant was obtained through the orthogonal experiment.The pH value of the detergent was 6.99,total active substance was 20.49％ and the content of EDTA was 5.99％.After being kept at-5 ℃ and 40℃℃ for 24h,the decontaminant showed no strange smell,no precipitation,no discoloration and still kept transparent.The decontamination effects on Co2+ and Mn2+ contaminated on hand skin were 103.13％ ± 0.05％ and 100.62％ ± 0.09％,respectively,which was significantly higher than that of distilled water (81.77％ ± 0.23％ and 79.63％ ± 0.23％,P＜0.01,respectively).Conclusion The decontaminant has a high effect on decontamination of Co2+ and Mn2+ polluted on skin,and is hopeful to be developed as an effective detergent on radioactive isotopes contamination.关键词
放射性沾染/去污剂/表面活性剂/EDTAKey words
radioactive contamination/decontaminant/surfactant/EDTA分类
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原维鸿,沈先荣,刘琼,何颖,陈伟,王庆蓉,罗群,侯登勇,唐雪..钴锰放射性核素皮肤沾染去污剂的初步研制[J].解放军医学杂志,2018,43(1):69-74,6.
