解放军医学杂志2018，Vol.43Issue(2)：135-139,5.DOI:10.11855/j.issn.0577-7402.2018.02.09
基于体表面积和体重的个体化对比剂方案在冠脉CT血管造影中的应用价值
The value of individualized contrast agent injection regimen in coronary CTA imaging based on body surface area and body weight
摘要
Abstract
Objective To explore the effect of individualized contrast agent injection regimen on coronary artery enhancement based on body surface area (BSA) and body weight (BW).Methods Totally 300 patients with suspected coronary heart disease from January to December 2016 in our hospital were randomly divided into three groups:control group (the injection volume and flow rate were fixed),BSA adjustment group and BW adjustment group.The patients were detected by CTA,and the degree and quality of coronary artery enhancement,the amount and flow rate of contrast agent,and the safety were analyzed in the three groups.Results The coronary artery enhancement value of the BSA adjustment group and the BW adjustment group was significantly higher than that of the control group (P＜0.05).The coronary enhancement in the BSA adjustment group was significantly higher than that of the BW adjustment group.Moreover,the standard deviation of the BSA adjustment group was significantly lower than that of the BW adjustment group (P＜0.05).The CTA score of the BSA adjustment group was significantly higher than that of the control group (P＜0.05).However,there was no significant difference between the BW adjustment group and BSA adjustment group or the control group (P＞0.05).The contrast agent dosage and flow rate was significantly higher in the control group than in the BSA adjustment group and BW adjustment group (P＜0.05).However,there was no significant difference between the BW adjustment group and BSA adjustment group (P＞0.05).Also,there was no significant difference in safety index between the three groups (P＞0.05).Conclusion The individualized contrast agent injection program based on BSA adjustment could not only reduce the amount of coronary imaging contrast agent and flow rate,but also improve the degree and effect of coronary artery enhancement.It could be expected to become a technical means for screening,early diagnosis,and even early intervention in early coronary heart disease.关键词
冠脉CT血管造影/体表面积/体重/造影剂/强化程度/强化效果Key words
coronary CT angiography/body surface area/body weight/contrast agent/enhanced degree/enhanced effect分类
医药卫生引用本文复制引用
杨琴,何其舟,余飞,张艳丽,斯光晏..基于体表面积和体重的个体化对比剂方案在冠脉CT血管造影中的应用价值[J].解放军医学杂志,2018,43(2):135-139,5.基金项目
四川省教育厅科研基金(17ZB0483)This work was supported by the Scientific Fundation of Education Department of Sichuan Province (17ZB0483) （17ZB0483）
