临床小儿外科杂志2018，Vol.17Issue(2)：99-105,7.DOI:10.3969/j.issn.1671-6353.2018.02.005
先天性巨结肠手术后近期并发症的发生率及危险因素分析
Prevalence and risk factors of the early complications after surgery of Hirschprung's disease:a retro-spective cohort study
摘要
Abstract
Objective To explore the prevalence and risk factors of early complications after surgery of Hirschprung's disease,provide a theoretical basis of diagnosis and treatment for the clinicians,and reducecom-plications.Methods Questionnaire surveys conducted on the Hirschprung's disease patients who underwent surgical procedure in our hospital from January 1,2002 to December 31,2012 were carried out.The patient's medical record data including the possible mid-,pre-or post-operation risk factors were carefully reviewed and analyzed by Logistic multiple factors analyses.Results The follow-up time was 1-13 years(mean 6.27 ± 2.85years).181 cases were obtained and 95(52.49%)proved to be suffered earlier postoperative complica-tions from surgery.The earlier postoperative complications included enterocolitis in 52(28.73%)cases,soiling and/or incontinence in 38(20.99%)cases,anastomotic stenosis in 2(1.10%)cases,prolapse in one (0.55%)cases,abdominal infection in one(0.55%)cases and one child was dead(0.55%).Logistic mul-tiple factors analysis showed that the risk factors of enterocolitis were low birth weight(OR=2.378),low IgA (OR=2.766),preoperative enterocolitis(OR=4.597)and aganglionic segment ≥30 cm(OR=3.285).The risk factors of soiling and/or incontinence included low birth weight(OR=3.006),low IgA(OR=3.885), aganglionic segment≥30 cm(OR=5.055)and operative age <2 months(OR=4.270).Conclusion En-terocolitis and soiling and/or incontinence were still the main earlier complications after surgery for Hirschprung's disease,clinicians and healthcare should strengthen the knowledge of the prevalence and risk fac -tors of these complications and take appropriate methods to reduce the incidence of these complications.关键词
Hirschsprung病/手术后并发症/发病率/危险因素Key words
Hirschsprung Disease/Postoperative Complications/Incidence/Risk Factors引用本文复制引用
黄文凯,李雪丽,张瑾,王维林,张树成..先天性巨结肠手术后近期并发症的发生率及危险因素分析[J].临床小儿外科杂志,2018,17(2):99-105,7.基金项目
国家自然科学基金(30700917) （30700917）
