临床小儿外科杂志2018，Vol.17Issue(2)：131-135,5.DOI:10.3969/j.issn.1671-6353.2018.02.011
儿童先天性巨痣的病理特征及手术疗效探讨
The discussion over pathological features and the effect of surgical treatment of children with giant pig-mented nevus
杨文 1周启星 1成琦 1韩崑 1张勇 1陈俊 1吴丁安 1樊利芳2
作者信息
- 1. 华中科技大学同济医学院附属武汉儿童医院(武汉 市妇幼保健院) 湖北省武汉市,430016
- 2. 武汉大学基础医学院病理教研室 湖北省武汉市,430071
- 折叠
摘要
Abstract
Objective To explore the association among surgical techniques,surgical timing and patho-logical features of children Giant Pigmented Nevus.Methods 28 cases with Giant Pigmented Nevus on chil-dren who were treated in our deparment from June 2009 to December 2014,were retrospectively analyzed.These cases include 18 males and 10 females,in which 13 cases on the head and face region and 15 cases on the body and limb region.The samples are stained by using HE staining.One case of infants with giant pigmented nevi inside the hairline was cured by two-stage operation with the skin expander;23 patients received full-thickness skin graft to fix the defect after excision of giant nevus;one case undertook resection surgery in different stages, with graft covering the wound;Three cases of older children undertook partial resection due to the large area of nevi,which was crossing the joints and lacking of enough skin for grafting.Results Resected giant nevus had better blood supply than the normal skin.Subcutaneous lipid was rare due to the association with the superficial fascia.HE staining pathological examination showed that 2 cases were melanocytes borderline nevus(7%),26 cases were compound nevus(93%),and no malignant change was occurred.In 28 cases,all the wounds were healed in I stage,and the healing was satisfactory.Conclusion Congenital giant nevus has the cellular biologi-cal characteristics of benign tumors,and early plastic surgery can effectively reduce the surgical scar.Surgery can better restore the shape and function of children,remove the area and need less tissue,and reduce the risk of malignant transformation in pathology,to a large extent,reduce the psychological harm of patients.关键词
痣/先天性/外科手术/治疗/病理/儿童Key words
Nevus/CN/Surgical Procedures/Operative/Therapy/Pathology/Child引用本文复制引用
杨文,周启星,成琦,韩崑,张勇,陈俊,吴丁安,樊利芳..儿童先天性巨痣的病理特征及手术疗效探讨[J].临床小儿外科杂志,2018,17(2):131-135,5.
