临床与实验病理学杂志2017，Vol.33Issue(12)：1316-1319,4.DOI:10.13315/j.cnki.cjcep.2017.12.005
胰腺实性假乳头状瘤临床病理学与术后复发/转移的相关性分析
Correlation of clinicopathologic features and postoperative recurrence or metastasis in solid-pseudopapillary neoplasms of the pancreas
摘要
Abstract
Purpose To explore the correlation between the clinicopathological features and postoperative recurrence or metastasis of solid-pseudopapillary neoplasms of the pancreas (SPN).Method The clinicopathological characteristics of 73 SPNs were summarized,the patients' prognosis were followed up by telephone and then the correlation of clinicopathological characteristics and recurrence or metastasis was analyzed.Results 57 female patients and 16 male patients were included in this study.The age range was 7 to 68 years old with the average of 28 and median age of 27.The mean diameter of the tumors was 6.47 cm (range 0.31～ 14 cm).30 cases of tumors were located in the head of pancreas,9 in the body of pancreas,and 33 in the tail of pancreas.One case was a multiple lesion simultaneously located in the body and the tail.All patients were followed up by telephone for mean time 34.8 months with the range of 12 ～ 99 months.Necrosis,calcification,cholesterol crystal,foamy histiocytes,nuclear atypia,pancreatic parenchymal invasion,and perineural invasion had no statistical significance between non-recurrent/metastatic group and recurrent/metastatic group.However,there was significant difference for extra-pancreatic invasion,angiovascular invasion and Ki-67 proliferation index between non-recurrent/metastatic group and recurrent /metastatic group.Conclusion Extra-pancreatic invasion,angiovascular invasion and Ki-67 proliferation index ≥ 4％ have reference significance for predicting recurrence or metastasis of SPN.关键词
胰腺肿瘤/实性假乳头状瘤/临床病理/复发/转移/预后Key words
pancreatic neoplasms/solid-pseudopapillary neoplasms/clinical pathology/recurrence/metastasis/prognosis分类
医药卫生引用本文复制引用
高汉青,庞霞,赵香田,王青杰,马怡晖..胰腺实性假乳头状瘤临床病理学与术后复发/转移的相关性分析[J].临床与实验病理学杂志,2017,33(12):1316-1319,4.基金项目
国家自然科学基金青年项目(81401936) （81401936）
