国际眼科杂志2018，Vol.18Issue(4)：642-644,3.DOI:10.3980/j.issn.1672-5123.2018.4.11
骨髓间充质干细胞治疗视网膜新生血管性疾病的研究进展
Research progress of the bone marrow mesenchymal stem cells to treat retinal neovascular disease
摘要
Abstract
·Retinal neovascular disease is not an independent eye disease,which is more common seen in many other eye diseases spontaneously and cause serious damage to vision, such as retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, retinal central venous obstruction and retina venous inflammation, which present retinal neovascularization. The loss of normal blood vessels structure and function, causing pathological bleeding,oozing,edema and retinal detachment and other pathological changes, they are the main reason for loss of vision, which has become a worldwide blindness disease. At present, the main treatment for the disease include of laser occlusion, vitrectomy, repeated vitreous cavity injection of anti-vascular endothelial growth factor, those treatment has significant curative effect, but cannot prevent relapse of the disease. There is still no long-term effective treatment method nowadays. The emergence of stem cell therapy has provided potential alternative therapies. In this review, the latest application of bone marrow mesenchymal stem cells (BMSCs) in retinal neovascular disease will be discussed and present its migration advantages and promising clinical application prospects.关键词
视网膜新生血管/血管内皮因子/干细胞移植/早产儿视网膜病变/糖尿病性视网膜病变Key words
retinal neovascularization/vascular endothelial growth factor/stem cell transplantation/retinopathy of prematurity/diabetic retinopathy引用本文复制引用
程伟靖,徐国兴..骨髓间充质干细胞治疗视网膜新生血管性疾病的研究进展[J].国际眼科杂志,2018,18(4):642-644,3.基金项目
国家自然科学基金资助项目(No.81770948) （No.81770948）
福建省社会发展高校产学合作项目(No.2014Y4003) Natural Science Foundation of China(No.81770948) （No.2014Y4003）
Industry-Academy Cooperation Project for Social Development of Fujian Province(No.2014Y4003) （No.2014Y4003）
